The Journal of general virology 2016 9 08() doi 10.1099/jgv.0.000601
A new simian retrovirus (SRV) subtype was discovered in China and the U.S. from Cambodian-origin cynomolgus monkeys. Histopathological examination from necropsied animals showed multifocal lymphoplasmacystic and histocytic inflammation. The complete genome sequences demonstrated that the U.S. virus isolates were nearly identical (99.91%-99.93%) and differed only slightly (99.13%-99.16% identical) from the China isolate. Phylogenetic analysis showed that the new virus isolates formed a distinct branch of SRV-1 through -7 and, therefore, were named this subtype SRV-8. This SRV-8 variant was also phylogenetically and serologically more closely related to SRV-4 than any other SRV subtype.