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Adsorption of viral particles from the blood plasma of patients with viral hepatitis on nanodiamonds.

Adsorption of viral particles from the blood plasma of patients with viral hepatitis on nanodiamonds.
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Baron AV, Osipov NV, Yashchenko SV, Kokotukha YA, Baron IJ, Puzyr AP, Olkhovskiy IA, Bondar VS,


Baron AV, Osipov NV, Yashchenko SV, Kokotukha YA, Baron IJ, Puzyr AP, Olkhovskiy IA, Bondar VS, (click to view)

Baron AV, Osipov NV, Yashchenko SV, Kokotukha YA, Baron IJ, Puzyr AP, Olkhovskiy IA, Bondar VS,

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Doklady. Biochemistry and biophysics 2016 09 07469(1) 244-6 doi 10.1134/S1607672916040037

Abstract

Adsorption of viral particles from the blood plasma of patients with viral hepatitis B and C on modified nanodiamonds (MNDs) was shown in the in vitro experiments. PCR method showed the treatment of plasma with MNDs leads to a decrease in the viral load by 2-3 orders of magnitude or more in both cases studied. These results make it possible to predict the applicability of MNDs for the development of new technologies of hemodialysis and plasmapheresis for binding and removal of viral particles from the blood of infected patients.

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