Lung Cancer

ATS 2013: Racial Disparities in NSCLC Surgery

The Particulars: Surgery is typically the indicated initial treatment of loco-regional non-small cell lung cancer (NSCLC). Data are lacking on how surgical management of NSCLC varies by race.

Data Breakdown: For a study, 1.2 million patients were assessed following their first course of treatment after an initial NSCLC diagnosis.…

‘Big Tent’ of Science, Medicine at ATS 2013

PHILADELPHIA — As the multiple disciplines that make up pulmonary, critical care, and sleep medicine gather here, the 2013 American Thoracic Society (ATS) International Conference will have a “big tent” atmosphere devoted to the needs of both clinical medicine and basic science.…

Obesity: A Challenge in Lung Cancer Surgery | News Brief

Among patients with primary lung cancer undergoing lobectomy, having a higher BMI appears to increase total operating room time. American investigators found that the average operating room time increased by 7.2 minutes for every 10-unit increase in BMI.

Abstract: Annals of Thoracic Surgery, December 2012.…

STS 2013: Identifying Small, High-Risk Lung Tumors | News Brief

The Particulars: Currently, there is no reliable method for identifying pathologically staged, node-negative non-squamous non-small cell lung cancers (NSCLC) smaller than 2 cm (T1a). As adoption of low-dose CT screening rapidly increases, it is possible that a novel molecular assay may help detect T1a node-negative tumors early.…

STS 2013: Feasibility Test of Volume Criteria for T Staging | News Brief

Purpose: Size criteria have been used as a gold standard for a long time in cancer staging of all kinds of solid tumors. However, real tumor mass is usually neither spherical nor symmetrical in shape. Therefore, single length (diameter) of tumor does not stand for the tumor volume exactly, because of its asymmetry and irregularity in shape.…

STS 2013: Tri-Modality Therapy for Superior Sulcus NSCLC | News Brief

Purpose: Trimodality therapy incorporating preoperative chemotherapy (cisplatin-etoposide, CisP/Etop), radiation, and surgery is generally considered the standard of care for Superior Sulcus (SS) cancers. Intergroup SWOG 9416 demonstrated 5-year survival of 44%, with relapse mainly in distant sites. To address this issue, S0220 was designed to substitute single-agent docetaxel (DTX) for CisP/Etop during the consolidation phase after surgery.…

Optimizing Resources in Lung Cancer Surgery | News Brief

Performing routine needle biopsy of suspicious lung nodules in surgical candidates appears to have several benefits, according to Canadian investigators. With routine needle biopsy, 16% of patients avoided operation and only 2.7% underwent resection of a pathologically benign nodule. Sensitivity, specificity, and positive and negative predictive values were 100%, 75%, 99.7%, and 100%, respectively.…

FDA Permits Marketing of Bio-Seal Lung Biopsy Tract Plug System | News Brief

Reduces risk of collapsed lung following lung biopsy…

CHEST 2012: Secondhand Smoke Can Impair Breathing Within Minutes | News Brief

Heavy concentrations of secondhand smoke, such as those found in smoke-filled bars and cars, can lead to airway restriction for bystanders within minutes of exposure. The study, presented at CHEST 2012, the annual meeting of the American College of Chest Physicians, showed that after 20 minutes of exposure to highly concentrated secondhand smoke, participants experienced near immediate physiologic changes, including airway resistance and impedance.…

FDA Approves Abraxane for Advanced NSCLC | News Brief

Celgene Corporation today announced the U.S. Food and Drug Administration (FDA) has approved Abraxane (paclitaxel protein-bound particles for injectable suspension) (albumin-bound) for the first-line treatment of locally advanced or metastatic non-small cell lung cancer, in combination with carboplatin, in patients who are not candidates for curative surgery or radiation therapy.…

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