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Orthopedics

Enhanced Osteolysis Targeted Therapy through Fusion of Exosomes Derived from M2 Macrophages and Bone Marrow Mesenchymal Stem Cells: Modulating Macrophage Polarization.

Oct 09, 2023

Aseptic loosening of prostheses is a highly researched topic, and wear particle-induced macrophage polarization is a significant cause of peri-prosthetic osteolysis. Exosomes derived from bone marrow ...

Sarcopenia Worsens Liver Transplant Outcomes for Patients With Cirrhosis

Oct 06, 2023

THURSDAY, Oct. 5, 2023 (HealthDay News) -- Sarcopenia is associated with adverse outcomes after liver transplantation (LT) in patients with decompensated cirrhosis (DC), according to a study published...

More Than 75,000 Kaiser Permanente Union Workers Go on Strike

Oct 05, 2023

WEDNESDAY, Oct. 4, 2023 (HealthDay News) -- Health care workers who serve millions of Americans began a three-day strike on Wednesday after contract negotiations over staffing levels stalled.More than...

Chatbots Generate Mostly Accurate Information to Medical Queries

Oct 05, 2023

WEDNESDAY, Oct. 4, 2023 (HealthDay News) -- Chatbots generate mostly accurate information to physician-developed medical queries, according to a study published online Oct. 2 in JAMA Network Open.Rach...

More Than 75,000 Kaiser Permanente Union Workers Could Strike on Wednesday

Oct 04, 2023

TUESDAY, Oct. 3, 2023 (HealthDay News) -- Health care workers who serve millions of Americans could strike Wednesday if Kaiser Permanente and union workers do not reach an agreement.More than 75,000 m...

Major Drug Companies Agree to Price Negotiations With U.S. Government

Oct 04, 2023

TUESDAY, Oct. 3, 2023 (HealthDay News) -- Pharmaceutical companies that make the 10 prescription drugs chosen to be the first for price negotiations for Medicare patients have agreed to talks with the...

Oral NSAIDs, Glucocorticoids Seem Effective for Hand Osteoarthritis

Oct 02, 2023

FRIDAY, Sept. 29, 2023 (HealthDay News) -- Oral nonsteroidal anti-inflammatory drugs (NASIDs) and glucocorticoids seem to be effective for hand osteoarthritis (OA), according to a review published onl...

Quantifying Success After First Revision Reverse Total Shoulder Arthroplasty: The Minimal and Substantial Clinically Important Percentage Of Maximal Possible Improvement.

Oct 02, 2023

When patients require reoperation after primary shoulder arthroplasty, revision reverse total shoulder arthroplasty (rTSA) is most commonly performed. However, defining clinically important improvemen...

Elbow hemiarthroplasty and total elbow arthroplasty provided a similar functional outcome for unreconstructable distal humeral fractures in patients aged 60 years or older: a multicenter randomized controlled trial.

Oct 02, 2023

Semiconstrained total elbow arthroplasty (TEA) is an established treatment for elderly patients with distal humeral fractures not amenable to stable internal fixation (unreconstructable). In recent ye...

"Waiting for the best day of your life". A qualitative interview study of patients' and clinicians' experiences of Perthes' disease.

Oct 02, 2023

Perthes' disease is an idiopathic avascular necrosis of the developing femoral head, often causing deformity that impairs physical function. Current treatments aim to optimize the joint reaction force...

More Progress Seen in Female Versus Minority Leadership Diversity in Medicine

Sep 28, 2023

WEDNESDAY, Sept. 27, 2023 (HealthDay News) -- Some specialties have made significant improvements in academic medial leadership diversity since 2007, according to a study published online Sept. 25 in ...

Machine Learning Model Can Predict Mortality After Hip Fracture

Sep 25, 2023

FRIDAY, Sept. 22, 2023 (HealthDay News) -- A machine learning model based on high-ranking biomarkers can predict mortality in patients with hip fracture, according to a study published online Sept. 20...

Changing Patterns of Zygomaticomaxillary Complex Fractures: A Retrospective Study.

Sep 25, 2023

Limited research exists regarding the incidence and variations of zygomaticomaxillary complex (ZMC) fracture patterns and their correlation with the mechanism of injury. Hence, further research is ind...

Relationships between frailty and exercise capacity in patients undergoing hemodialysis: A cross-sectional study.

Sep 25, 2023

Hemodialysis (HD) patients have a high prevalence of frailty. The association between frailty and exercise capacity in HD patients has not been established. This study aimed to clarify the relationshi...

Sclerotic-type chronic graft-versus-host disease exhibits activation of Th1 and OX40 cytokines.

Sep 25, 2023

Sclerotic-type cutaneous chronic graft-versus-host disease (ScGvHD) is a severe complication of allogeneic hematopoietic stem cell transplantation, with profound morbidity. A dearth of effective, targ...

Klotho overexpression is frequently associated with upstream rearrangements in fusion-negative phosphaturic mesenchymal tumors of bone and sinonasal tract.

Sep 25, 2023

Phosphaturic mesenchymal tumors (PMT) are uncommon neoplasms that cause hypophosphatemia/osteomalacia mainly by secreting fibroblast growth factor 23. We previously identified FN1::FGFR1/FGF1 fusions ...

Electronic Health Record Usability Tied to Patient Safety

Sep 20, 2023

TUESDAY, Sept. 19, 2023 (HealthDay News) -- There is a positive association between frontline user-rated electronic health record (EHR) usability and EHR safety performance, according to a study publi...

Use of Nonselective β-Blockers Tied to Lower Risk for Total Knee Arthroplasty

Sep 18, 2023

FRIDAY, Sept. 15, 2023 (HealthDay News) -- The use of nonselective β-blockers is associated with a lower likelihood of undergoing total knee arthroplasty (TKA), according to a study published online ...

Receipt of PT, Chiropractic Care Reportedly Low for Comorbid Chronic LBP, Opioid Use Disorder

Sep 14, 2023

WEDNESDAY, Sept. 13, 2023 (HealthDay News) -- For Medicare beneficiaries with chronic low back pain (CLBP) and opioid use disorder (OUD), receipt of physical therapy (PT) and chiropractic care is low ...

Small Changes in Bone Mineral Density Can Reduce Hip Fracture Risk

Sep 11, 2023

FRIDAY, Sept. 8, 2023 (HealthDay News) -- Small changes in bone mineral density (BMD) across populations can lead to a reduction in the incidence of hip fractures, according to a study published onlin...

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