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humira-abstracts

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Intolerance of dolutegravir-containing combination antiretroviral therapy regimens in real-life clinical practice.

AIDS (London, England) 30(18) 2831-2834 Abstract OBJECTIVE Dolutegravir (DGV) is one of the preferred antiretroviral agents in first-line combination antiretroviral therapy (cART). Though considered to be a

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Lead discovery for mammalian elongation of long chain fatty acids family 6 using a combination of high-throughput fluorescent-based assay and RapidFire mass spectrometry assay.

Biochemical and biophysical research communications 2016 10 26480(4) 721-726 pii S0006-291X(16)31789-2 Abstract A high-throughput RapidFire mass spectrometry assay is described for elongation of very long-chain fatty acids

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COPD, emphysema and the onset of lung cancer. A systematic review.

Cancer letters 2016 9 22382(2) 240-244 pii S0304-3835(16)30544-4 Abstract Chronic Obstructive Pulmonary Disease (COPD) and emphysema have been described as possible risk factors for lung cancer. We

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Staurosporine as an agonist for induction of GLUT4 translocation, identified by a pH-sensitive fluorescent IRAP-mOrange2 probe.

Biochemical and biophysical research communications 2016 10 18480(4) 534-538 pii S0006-291X(16)31734-X Abstract Insulin-stimulated GLUT4 translocation from GLUT4 storage vesicles (GSVs) to the plasma membrane (PM) constitutes a

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Hydroxytyrosol: a new class of microbicide displaying broad anti-HIV-1 activity.

AIDS (London, England) 30(18) 2767-2776 Abstract OBJECTIVE To investigate the toxicity and activity against HIV of 5-hydroxytyrosol as a potential microbicide. DESIGN The anti-HIV-1 activity of 5-hydroxytyrosol,

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Increasing prevalence of K65K and K66K in HIV-1 subtype B reverse transcriptase.

AIDS (London, England) 30(18) 2787-2793 Abstract OBJECTIVE Synonymous substitutions K65K/K66K in HIV-1 reverse transcriptase alleviate fitness and fidelity defects in HIV-1 molecular clones harboring thymidine analogue mutations

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Reduced bacterial skin infections in HIV-infected African children randomized to long-term cotrimoxazole prophylaxis.

AIDS (London, England) 30(18) 2823-2829 Abstract OBJECTIVE To evaluate whether cotrimoxazole prophylaxis prevents common skin conditions in HIV-infected children. DESIGN Open-label randomized controlled trial of continuing versus

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Long-term body composition changes in antiretroviral-treated HIV-infected individuals.

AIDS (London, England) 30(18) 2805-2813 Abstract OBJECTIVE Body composition impacts physical function and mortality. We compared long-term body composition changes after antiretroviral therapy (ART) initiation in HIV-infected

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Hormonal therapy with estradiol and drospirenone improves endothelium-dependent vasodilation in the coronary bed of ovariectomized spontaneously hypertensive rats.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2016 Nov 1749(1) e4655 doi 10.1590/1414-431X20154655 Abstract Drospirenone (DRSP) is a progestin

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Potentially Preventable Deaths Among the Five Leading Causes of Death – United States, 2010 and 2014.

MMWR. Morbidity and mortality weekly report 2016 Nov 1865(45) 1245-1255 doi 10.15585/mmwr.mm6545a1 Abstract Death rates by specific causes vary across the 50 states and the District of

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Inhibition of STAT Pathway Impairs Anti-Hepatitis C Virus Effect of Interferon Alpha.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016 Nov 1840(1-2) 77-90 Abstract BACKGROUND/AIMS Signal transducer and activator of transcription (STAT)

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Targeting a Novel RNA-Protein Interaction for Therapeutic Intervention of Hantavirus Disease.

The Journal of biological chemistry 2016 Oct 12291(47) 24702-24714 Abstract An evolutionarily conserved sequence at the 5′ terminus of hantaviral genomic RNA plays an important role in

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Relationships between 24-h blood pressure variability and 24-h central arterial pressure, pulse wave velocity and augmentation index in hypertensive patients.

Hypertension research : official journal of the Japanese Society of Hypertension 2016 11 24() doi 10.1038/hr.2016.156 Abstract Twenty-four-h blood pressure variability (BPV) predicts cardiovascular complications in hypertension,

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The prognostic value of measurement of high-sensitive cardiac troponin T for mortality in a cohort of stable chronic obstructive pulmonary disease patients.

BMC pulmonary medicine 2016 11 2516(1) 164 Abstract BACKGROUND Cardiovascular disease (CVD) is a common comorbidity in chronic obstructive pulmonary disease (COPD). Cardiac troponin (cTn) elevation, indicating

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Chronic pain in older adults: prevalence, incidence, and risk factors.

Scandinavian journal of rheumatology 2016 11 25() 1-9 Abstract OBJECTIVES Chronic pain is common in older adults, yet little is known of its development and the factors

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Leptospirosis-Associated Severe Pulmonary Hemorrhagic Syndrome with Lower Back Pain as an Initial Symptom.

The American journal of case reports 2016 11 2417() 883-886 Abstract BACKGROUND Leptospirosis is a zoonosis transmitted through urine of infected animals. Symptoms range from mild influenza-like

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Gastrodin protects against chronic inflammatory pain by inhibiting spinal synaptic potentiation.

Scientific reports 2016 Nov 176() 37251 doi 10.1038/srep37251 Abstract Tissue injury is known to produce inflammation and pain. Synaptic potentiation between peripheral nociceptors and spinal lamina I

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Assessment of Olfactory Function in MAPT-Associated Neurodegenerative Disease Reveals Odor-Identification Irreproducibility as a Non-Disease-Specific, General Characteristic of Olfactory Dysfunction.

PloS one 2016 Nov 1711(11) e0165112 doi 10.1371/journal.pone.0165112 Abstract Olfactory dysfunction is associated with normal aging, multiple neurodegenerative disorders, including Parkinson’s disease, Lewy body disease and Alzheimer’s

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Poor sleep in middle-aged women is not associated with menopause per se.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2016 Nov 1749(1) e4718 doi 10.1590/1414-431X20154718 Abstract Whether sleep problems of menopausal

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Etiology and Management of Raised Intraocular Pressure following Posterior Chamber Phakic Intraocular Lens Implantation in Myopic Eyes.

PloS one 2016 Nov 1711(11) e0165469 doi 10.1371/journal.pone.0165469 Abstract AIM To evaluate the etiology and management of elevated intraocular pressure (IOP) following posterior chamber phakic implantable collamer

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