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Do Memory CD4 T Cells Keep Their Cell-Type Programming: Plasticity versus Fate Commitment? Complexities of Interpretation due to the Heterogeneity of Memory CD4 T Cells, Including T Follicular Helper Cells.

Cold Spring Harbor perspectives in biology 2017 04 21() pii 10.1101/cshperspect.a032102 Abstract Plasticity is the ability of a cell type to convert to another cell type. There

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Effects of Antiretroviral Therapy and Depressive Symptoms on All-Cause Mortality Among HIV-Infected Women.

American journal of epidemiology 2017 04 18() 1-10 doi 10.1093/aje/kww192 Abstract Depression affects up to 30% of human immunodeficiency virus (HIV)-infected individuals. We estimated joint effects of

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Uveitis in Siriraj Hospital: pattern differences between immune-related uveitis and infectious uveitis in a university-based tertiary care hospital.

International ophthalmology 2017 04 20() doi 10.1007/s10792-017-0515-5 Abstract PURPOSE To describe a proportion of uveitis and to analyse differences between immune-related uveitis and infectious uveitis groups. METHODS

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Virological success after 12 and 24 months of antiretroviral therapy in sub-Saharan Africa: Comparing results of trials, cohorts and cross-sectional studies using a systematic review and meta-analysis.

PloS one 2017 04 2012(4) e0174767 doi 10.1371/journal.pone.0174767 Abstract BACKGROUND UNAIDS recently defined the 90-90-90 target as a way to end the HIV epidemic. However, the proportion

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The Yin and Yang of Autism Genetics: How Rare De Novo and Common Variations Affect Liability.

Annual review of genomics and human genetics 2017 04 19() doi 10.1146/annurev-genom-083115-022647 Abstract The etiology of autism spectrum disorder (ASD) is complex, involving both genetic and environmental

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Virion associated Vpr alleviates a post-integration block to HIV-1 infection of dendritic cells.

Journal of virology 2017 04 19() pii 10.1128/JVI.00051-17 Abstract Viral protein R (Vpr) is an HIV-1 accessory protein whose function remains poorly understood. In this report, we

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India passes law prohibiting discrimination against people with HIV/AIDS.

BMJ (Clinical research ed.) 2017 04 21357() j1973 doi 10.1136/bmj.j1973 Abstract

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Kaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latency.

PLoS pathogens 2017 04 2113(4) e1006335 doi 10.1371/journal.ppat.1006335 Abstract Kaposi Sarcoma Herpesvirus (KSHV), a γ2-herpesvirus and class 1 carcinogen, is responsible for at least three human malignancies:

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Proton Chemical Shift Imaging Study of the Combined Antiretroviral Therapy Impact on Neurometabolic Parameters in Chronic HIV Infection.

AJNR. American journal of neuroradiology 2017 04 20() doi 10.3174/ajnr.A5160 Abstract BACKGROUND AND PURPOSE The introduction of combination antiretroviral therapy has failed to reduce the high prevalence

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Correction: Risk factors associated with sexually transmitted infections among HIV infected men who have sex with men.

PloS one 2017 04 2012(4) e0176579 doi 10.1371/journal.pone.0176579 Abstract [This corrects the article DOI: 10.1371/journal.pone.0170635.].

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Preclinical Development of BCG.HIVA(2auxo.int), Harboring an Integrative Expression Vector, for a HIV-TB Pediatric vaccine. Enhancement of Stability and Specific HIV-1 T-cell Immunity.

Human vaccines & immunotherapeutics 2017 04 20() 0 doi 10.1080/21645515.2017.1316911 Abstract One of the critical issues that should be addressed in the development of a BCG-based HIV

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Subtype-Specific Differences in Gag-Protease-Driven Replication Capacity are Consistent with Inter-Subtype Differences in HIV-1 Disease Progression.

Journal of virology 2017 04 19() pii 10.1128/JVI.00253-17 Abstract There are marked differences in the spread and prevalence of HIV-1 subtypes worldwide, and differences in clinical progression

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Racial disparities in HIV.

The lancet. HIV 2017 04 18() pii 10.1016/S2352-3018(17)30064-4 Abstract

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Structure based design of a new scaffold for cell-penetrating peptidic inhibitors of the histone demethylase PHF8.

Chembiochem : a European journal of chemical biology 2017 04 21() doi 10.1002/cbic.201700109 Abstract The histone demethylase PHF8 catalyzes demethylation of mono- and di-methylated lysine 9 on

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Dihydrolipoamide dehydrogenase-Lpd (Rv0462)-specific T cell recall responses are higher in healthy household contacts of TB: a novel immunodominant antigen from M. tuberculosis.

Journal of leukocyte biology 2017 04 20() pii 10.1189/jlb.4A0916-067RR Abstract The partial effectiveness against pulmonary tuberculosis (PTB), displayed by the existing tuberculosis (TB) vaccine, bacillus Calmette-Guérin (BCG),

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Dendritic cell maturation, but not type I interferon exposure, restricts infection by HTLV-1, and viral transmission to T-cells.

PLoS pathogens 2017 04 2013(4) e1006353 doi 10.1371/journal.ppat.1006353 Abstract Human T lymphotropic Virus type 1 (HTLV-1) is the etiological agent of Adult T cell Leukemia/Lymphoma (ATLL) and

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Parameter Optimization for Interaction between C-Terminal Domains of HIV-1 Capsid Protein.

Journal of chemical information and modeling 2017 04 20() doi 10.1021/acs.jcim.7b00011 Abstract HIV-1 capsid proteins (CAs) assemble into a capsid that encloses the viral RNA. The binding

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Simian Immunodeficiency Virus Targeting of CXCR3(+) CD4(+) T Cells in Secondary Lymphoid Organs Is Associated with Robust CXCL10 Expression in Monocyte/Macrophage Subsets.

Journal of virology 2017 04 19() pii 10.1128/JVI.00439-17 Abstract Glycosylation of Env defines pathogenic properties of SIV. We previously demonstrated that pathogenic SIVmac239 and live-attenuated, quintuple deglycosylated

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Sources of racial disparities in HIV prevalence in men who have sex with men in Atlanta, GA, USA: a modelling study.

The lancet. HIV 2017 04 18() pii 10.1016/S2352-3018(17)30067-X Abstract BACKGROUND In the USA, men who have sex men (MSM) are at high risk for HIV, and black

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Significant reductions in alcohol use after Hepatitis C treatment: Results from the French ANRS CO13-HEPAVIH cohort.

Addiction (Abingdon, England) 2017 04 21() doi 10.1111/add.13851 Abstract BACKGROUND AND AIMS Few data exist on changes to substance use patterns before and after hepatitis C virus

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