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Characterizing HIV-1 Splicing by Using Next-Generation Sequencing.

Journal of virology 2017 02 2891(6) pii 10.1128/JVI.02515-16 Abstract Full-length human immunodeficiency virus type 1 (HIV-1) RNA serves as the genome or as an mRNA, or this

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Synthesis, Antiviral Potency, in Vitro ADMET, and X-ray Structure of Potent CD4 Mimics as Entry Inhibitors That Target the Phe43 Cavity of HIV-1 gp120.

Journal of medicinal chemistry 2017 03 16() doi 10.1021/acs.jmedchem.7b00179 Abstract In our attempt to optimize the lead HIV-1 entry antagonist, NBD-11021, we present in this study the

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Clinical and computed tomography findings in Chinese lung cancer patients with HIV infection: A multi-center study.

Thoracic cancer 2017 03 15() doi 10.1111/1759-7714.12429 Abstract BACKGROUND The study was conducted to investigate clinical and computed tomography (CT) features in Chinese lung cancer patients with

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HTLV-1 induces a Th1-like state in CD4(+)CCR4(+) T cells that produces an inflammatory positive feedback loop via astrocytes in HAM/TSP.

Journal of neuroimmunology 2016 08 12304() 51-55 pii 10.1016/j.jneuroim.2016.08.012 Abstract The main feature of Human T-lymphotropic virus type I (HTLV-1) -associated myelopathy/tropical spastic paraparesis (HAM/TSP) pathogenesis is

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Estimated Perinatal HIV Infection Among Infants Born in the United States, 2002-2013.

JAMA pediatrics 2017 03 20() doi 10.1001/jamapediatrics.2016.5053 Abstract Importance Perinatal transmission of human immunodeficiency virus (HIV) can be reduced through services including antiretroviral treatment and prophylaxis. Data

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Fertility and HIV following universal access to ART in Rwanda: a cross-sectional analysis of Demographic and Health Survey data.

Reproductive health 2017 03 1414(1) 40 doi 10.1186/s12978-017-0301-x Abstract BACKGROUND HIV infection is linked to decreased fertility and fertility desires in sub-Saharan Africa due to biological and

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Development and validation of a liquid chromatography-MS/MS method for simultaneous quantification of tenofovir and efavirenz in biological tissues and fluids.

Journal of pharmaceutical and biomedical analysis 2016 12 27136() 120-125 pii 10.1016/j.jpba.2016.12.028 Abstract Millions of people worldwide live with human immunodeficiency virus (HIV) infection thus justifying the

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Experience of using ISGTL-2 in patients with DM2 and HIV infection.

European journal of internal medicine 2017 03 15() pii 10.1016/j.ejim.2017.03.002 Abstract

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Blacks Still Trail in HIV Care.

JAMA 317(10) 1010 doi 10.1001/jama.2017.1194 Abstract

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Enzymatic synthesis of a novel kaempferol-3-O-β-D-glucopyranosyl-(1→4)-O-α-D-glucopyranoside using cyclodextrin glucanotransferase, and its inhibitory effects on aldose reductase, inflammation, and oxidative stress.

Journal of agricultural and food chemistry 2017 03 16() doi 10.1021/acs.jafc.7b00501 Abstract Kaempferol-3-O-β-D-glucopyranoside (astragalin, AS), a major flavonoid that exists in various plants, exerts anti-oxidant, anti-tumor, anti-human

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Guidelines in lower-middle income countries.

British journal of haematology 2017 03 14() doi 10.1111/bjh.14583 Abstract Guidelines include recommendations intended to optimize patient care; used appropriately, they make healthcare consistent and efficient. In

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Inhibitors of STAT3, β-catenin, and IGF-1R sensitize mouse PIK3CA mutant breast cancer to PI3K inhibitors.

Molecular oncology 2017 03 15() doi 10.1002/1878-0261.12053 Abstract Although mutations in the phosphoinositide 3-kinase-catalytic subunit (PIK3CA) are common in breast cancer, PI3K inhibitors alone have shown modest

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High-throughput sequencing identifies HIV-1-replication- and latency-related miRNAs in CD4(+) T cell lines.

Archives of virology 2017 03 16() doi 10.1007/s00705-017-3305-5 Abstract MicroRNAs are potent gene expression regulators involved in regulating various biological processes, including host-pathogen interactions. In this study,

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Genotypic characterization of human immunodeficiency virus type 1 derived from antiretroviral drug-treated individuals residing in earthquake-affected areas in Nepal.

AIDS research and human retroviruses 2017 03 16() doi 10.1089/AID.2017.0047 Abstract Molecular epidemiological data on human immunodeficiency virus type 1 (HIV-1) are limited in Nepal, and has

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ArtA-Dependent Processing of a Tat Substrate Containing a Conserved Tripartite Structure That Is Not Localized at the C Terminus.

Journal of bacteriology 2017 03 14199(7) pii 10.1128/JB.00802-16 Abstract Most prokaryote-secreted proteins are transported to the cell surface using either the general secretion (Sec) or twin-arginine translocation

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Simple screening for neurocognitive impairment in routine HIV outpatient care: is it deliverable?

AIDS care 2017 03 14() 1-5 doi 10.1080/09540121.2017.1300632 Abstract Routine screening for psychological and cognitive difficulties is recommended in BHIVA guidelines but screening questions are not specified

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Corticosteroids for tuberculous pleurisy.

The Cochrane database of systematic reviews 2017 03 143() CD001876 doi 10.1002/14651858.CD001876.pub3 Abstract BACKGROUND Corticosteroids used in addition to antituberculous therapy have been reported to benefit people

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Long-Acting Antiretrovirals: Where Are We now?

Current HIV/AIDS reports 2017 03 16() doi 10.1007/s11904-017-0353-0 Abstract PURPOSE OF REVIEW Current HIV treatment options require daily use of combination antiretroviral drugs. Many persons living with

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Heteromer Induction: An Approach to Unique Pharmacology?

ACS chemical neuroscience 2017 01 318(3) 426-428 doi 10.1021/acschemneuro.7b00002 Abstract It is proposed that two types of opioid receptor heteromers exist: a) those that are constitutive and

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Evaluation of mHealth strategies to optimize adherence and efficacy of Option B+ prevention of mother-to-child HIV transmission: Rationale, design and methods of a 3-armed randomized controlled trial.

Contemporary clinical trials 2017 03 14() pii 10.1016/j.cct.2017.03.007 Abstract

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