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Diabetes mellitus among HIV-infected individuals in follow-up care at University of Gondar Hospital, Northwest Ethiopia.

Diabetes mellitus among HIV-infected individuals in follow-up care at University of Gondar Hospital, Northwest Ethiopia.
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Abebe SM, Getachew A, Fasika S, Bayisa M, Girma Demisse A, Mesfin N,


Abebe SM, Getachew A, Fasika S, Bayisa M, Girma Demisse A, Mesfin N, (click to view)

Abebe SM, Getachew A, Fasika S, Bayisa M, Girma Demisse A, Mesfin N,

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BMJ open 2016 08 186(8) e011175 doi 10.1136/bmjopen-2016-011175

Abstract
OBJECTIVE
To assess the prevalence of diabetes mellitus (DM) and associated factors among HIV-infected adults in northwest Ethiopia.

DESIGN
Hospital-based cross-sectional study.

SETTING
HIV clinic of the University of Gondar Hospital, Ethiopia.

PARTICIPANTS
All HIV-infected adults who visited the HIV clinic from December 2013 to the end of February 2014 were the source population.

MEASURES
A structured and pretested questionnaire incorporating the WHO STEPwise approach was used. A multivariate logistic regression analysis was applied to assess factors associated with DM.

RESULTS
The overall prevalence of type 2 DM was 8% (95% CI 5.5% to 10.5%). The prevalence of DM was higher (13.2%; 95% CI 8.0% to 18.3%) among subjects receiving pre-antiretroviral treatment (pre-ART) than among those taking ART (5.1%; 95% CI 2.6% to 7.6%). Thirteen (35.1%) of the DM cases were newly identified during the study. Obesity (adjusted OR (AOR) 6.55; 1.20 to 35.8), hypertension (AOR 3.45; 1.50 to 7.90), being in the pre-ART group (AOR 4.47; 1.80 to 11.08), hypertriglyceridaemia (AOR 2.24; 1.02 to 49.5) and tertiary-level education (AOR 11.8; 2.28 to 61.4) were associated with DM.

CONCLUSIONS
Overall DM prevalence was high, particularly among subjects in the pre-ART group. More educated, hypertensive and obese HIV-infected adults were more likely to have DM as a comorbidity. Health policy and the clinical management of HIV-infected individuals should take into account the rising DM.

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