MONDAY, Sept. 26, 2016 (HealthDay News) — Patients with chronic rhinosinusitis (CRS) undergoing endoscopic sinus surgery (ESS) experience improvements in asthma quality-of-life (QOL) and asthma control, according to a study published online Sept. 17 in Allergy.
Rodney J. Schlosser, M.D., from the Medical University of South Carolina in Charleston, and colleagues conducted a prospective study involving 86 patients with CRS, with and without polyps and comorbid asthma. Participants completed the Mini-Asthma QOL Questionnaire (miniAQLQ) and Asthma Control Test (ACT) at baseline and six months postoperatively.
The researchers found that patients undergoing ESS reported improved scores on the miniAQLQ (P = 0.002) and ACT (P = 0.025). Fifty-one percent of patients undergoing ESS had uncontrolled baseline asthma; for these patients, ESS resulted in a minimal clinically important difference 57 and 50 percent of the time for miniAQLQ scores and ACT scores, respectively. Baseline miniAQLQ scores were worse in patients with comorbid allergy and chronic obstructive pulmonary disease (COPD), while baseline ACT scores were worse for patients with COPD. Preoperative corticosteroid dependency and change in total 22-item SinoNasal Outcome Test score were associated with changes in miniAQLQ scores after ESS (P = 0.011 and 0.010, respectively). Obstructive sleep apnea was associated with significantly less improvement in ACT scores (P = 0.016).
“Approximately half of patients with uncontrolled asthma improve after ESS, yet there are few CRS-specific factors associated with asthma QOL or control or ESS outcomes,” the authors write.
Two authors disclosed financial ties to the medical device and medical technology industries.
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