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Global challenges in human immunodeficiency virus and syphilis co-infection among men who have sex with men.

Global challenges in human immunodeficiency virus and syphilis co-infection among men who have sex with men.
Author Information (click to view)

Roberts CP, Klausner JD,


Roberts CP, Klausner JD, (click to view)

Roberts CP, Klausner JD,

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Expert review of anti-infective therapy 2016 9 14()

Abstract
INTRODUCTION
Syphilis and human immunodeficiency virus (HIV) co-infection disproportionately affects men who have sex with men (MSM), and the rate of co-infection has been increasing over the last decade. HIV and syphilis co-infection is particularly challenging because the infections interact synergistically thereby increasing the risk of acquisition and transmission as well as accelerating disease progression.

AREAS COVERED
This paper reviews and summarizes the epidemiology, pathogenesis, diagnosis, clinical management and prevention of HIV and syphilis co-infection among MSM. Expert Commentary: Research does not support a different syphilis treatment for co-infected individuals; however, co-infection may warrant a recommendation for antiretroviral therapy. In order to reverse the epidemic of syphilis and HIV co-infection, there needs to be greater awareness, improved cultural sensitivity among health care providers, improved access to preventative services and increased screening for syphilis and HIV.

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