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In utero exposure to NELFINAVIR-EMS.

In utero exposure to NELFINAVIR-EMS.
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Hleyhel M, Goujon S, Sibiude J, Blanche S, Warszawski J, ,


Hleyhel M, Goujon S, Sibiude J, Blanche S, Warszawski J, , (click to view)

Hleyhel M, Goujon S, Sibiude J, Blanche S, Warszawski J, ,

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AIDS (London, England) 2016 9 20()

Abstract

Ethyl methyl sulfone (EMS) contained in nelfinavir between 2007 and 2008 accidentally exposed embryos and fetuses to a powerful mutagen. We report data for 101 HIV-uninfected children exposed in utero included in the French prospective national cohort. The incidence of malformation was similar to that in the cohort as a whole with different drug exposures; no children had developed cancer after 9 years of follow up.

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