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Near Full-Length Genome Identification of a Novel HIV-1 Unique (B/C) Recombinant Isolate in Sichuan, China.

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Wang Y, Ma L, Xu W, Li F, Feng Y, Liang S, Shao Y, Zhang F,


Wang Y, Ma L, Xu W, Li F, Feng Y, Liang S, Shao Y, Zhang F, (click to view)

Wang Y, Ma L, Xu W, Li F, Feng Y, Liang S, Shao Y, Zhang F,

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AIDS research and human retroviruses 2016 6 22()

Abstract

A novel HIV-1 unique recombinant virus (XC2014EU20) was identified here, which was isolated from a HIV-positive man who infected through heterosexual in Sichuan, China. The near full-length genome analyses showed that the novel recombinant composed of three subtype B regions in a subtype C backbone. Different from the other CRFs and URFs, six recombinant break-points of XC2014EU20 with seven fragments were observed in the pol, vpu and nef genes, respectively. The emergence of B/C recombinant strain indicates the increasing complexity of the HIV-1 epidemic in Sichuan, China.

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