Conference Highlights: CROI 2011

This feature highlights some of the studies that emerged from the 2011 CROI annual conference, including the protective effects of circumcision against HIV, treatment of HIV-tuberculosis coinfection, and research on HIV-resistant T cells. » Circumcision Provides Protection Against HIV » Prompt Treatment Needed for HIV-TB Coinfection » Nurse Care Effective in HIV Management » Optimism on HIV-Resistant T Cells  Circumcision Provides Protection Against HIV The Particulars: Previous research has suggested that circumcising men may help protect them in the future from contracting the HIV virus. Findings from recent original randomized trials have suggested that circumcision reduces the risk of catching HIV by about 50%. Clinicians have expressed some concern about the effect of male circumcision on changing sexual behaviors and the adoption of more risk practices. A study was conducted to see how circumcision affects both the risk of HIV and human behavior. Data Breakdown:Researchers found that HIV incidence was 73% lower among trial participants who were circumcised and those who got circumcised later when compared with those in a control arm who did not accept circumcision. Researchers offered men in the control arm the chance to be circumcised, and 80.4% accepted. Among control participants who were circumcised, the risk of HIV was reduced 67%, compared with the men who declined the procedure. In post-trial surveillance, the study group observed no change in the number of non-marital sex partners between intervention and control patients. There was also no significant difference in condom use between the 1,321 men who got circumcised and the 372 who did not. Take Home Pearls: The benefit of male circumcision for HIV prevention appears to persist, even...