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Thalidomide in Refractory Tuberculomas and Pseudo-Abscesses.

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Viel-Thériault I, Thibeault R, Boucher FD, Drolet JP,


Viel-Thériault I, Thibeault R, Boucher FD, Drolet JP, (click to view)

Viel-Thériault I, Thibeault R, Boucher FD, Drolet JP,

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The Pediatric infectious disease journal 2016 6 21()

Abstract

Paradoxical immune reconstitution inflammatory syndrome (IRIS) is a well described entity even in immunocompetent children, principally in association with Mycobacterium tuberculosis infections. Central nervous system involvement is a potential life-threatening form, sometimes refractory to standard treatment. We report the case of an HIV-negative refugee teenager, who presented with brain tuberculomas and pseudo-abscesses responsive only to thalidomide.

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