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The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework.

The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework.
Author Information (click to view)

Alcock KJ, Abubakar A, Newton CR, Holding P,


Alcock KJ, Abubakar A, Newton CR, Holding P, (click to view)

Alcock KJ, Abubakar A, Newton CR, Holding P,

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BMC research notes 2016 Oct 129(1) 463

Abstract
BACKGROUND
HIV infection has been associated with impaired language development in prenatally exposed children. Although most of the burden of HIV occurs in sub-Saharan Africa, there have not been any comprehensive studies of HIV exposure on multiple aspects of language development using instruments appropriate for the population.

METHODS
We compared language development in children exposed to HIV in utero to community controls (N = 262, 8-30 months) in rural Kenya, using locally adapted and validated communicative development inventories.

RESULTS
The mean score of the younger HIV-exposed uninfected infants (8-15 months) was not significantly below that of the controls; however older HIV-exposed uninfected children had significantly poorer language scores, with HIV positive children scoring more poorly than community controls, on several measures.

CONCLUSIONS
Our preliminary data indicates that HIV infection is associated with impaired early language development, and that the methodology developed would be responsive to a more detailed investigation of the variability in outcome amongst children exposed to HIV, irrespective of their infection status.

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