Advertisement

 

 

The Interplay of Host Immunity, Environment and the Risk of Bacterial Vaginosis and Associated Reproductive Health Outcomes.

The Interplay of Host Immunity, Environment and the Risk of Bacterial Vaginosis and Associated Reproductive Health Outcomes.
Author Information (click to view)

Murphy K, Mitchell CM,


Murphy K, Mitchell CM, (click to view)

Murphy K, Mitchell CM,

Advertisement
Share on FacebookTweet about this on TwitterShare on LinkedIn

The Journal of infectious diseases 2016 04 07214 Suppl 1() S29-35 doi 10.1093/infdis/jiw140

Abstract

Bacterial vaginosis (BV) is one of the most common causes of vaginal symptoms in US women, but its causal mechanism has not yet been defined. BV is more prevalent in women who are immunosuppressed, and several risk factors for the development of BV are associated with lower quantities of immune mediators in vaginal fluid. In contrast, the poor reproductive health outcomes associated with BV, such as preterm birth and human immunodeficiency virus type 1 acquisition, are associated with increased levels of proinflammatory immune mediators in the genital tract. In this article, we discuss how variations in the host immune profile and environmental effects on host immunity may influence the risk of BV, as well as the risk of complications associated with BV.

Submit a Comment

Your email address will not be published. Required fields are marked *

13 + eight =

[ HIDE/SHOW ]