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Willingness of human immunodeficiency virus-positive patients to donate their organs for transplantation in Taiwan: a cross-sectional questionnaire survey.

Willingness of human immunodeficiency virus-positive patients to donate their organs for transplantation in Taiwan: a cross-sectional questionnaire survey.
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Lee YC, Hung CC, Cheng A, Liu WC, Wu PY, Yang SP, Zhang JY, Luo YZ, Chang HY, Sun HY, Chang SC,


Lee YC, Hung CC, Cheng A, Liu WC, Wu PY, Yang SP, Zhang JY, Luo YZ, Chang HY, Sun HY, Chang SC, (click to view)

Lee YC, Hung CC, Cheng A, Liu WC, Wu PY, Yang SP, Zhang JY, Luo YZ, Chang HY, Sun HY, Chang SC,

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Transplant infectious disease : an official journal of the Transplantation Society 2016 9 24() doi 10.1111/tid.12614

Abstract
BACKGROUND
With the introduction of combination antiretroviral therapy (cART) that has significantly improved survival, human immunodeficiency virus (HIV)-positive patients may be potential organ donors to HIV-positive recipients in a few countries. Organ shortage remains a challenge for organ transplantation in Taiwan, where organ donation by HIV-positive patients remains prohibited by law.

METHODS
We assessed the willingness of organ donation (should they be pronounced brain death, and the ban on HIV-positive organ donation be lifted) among HIV-positive patients who received regular HIV care at a university hospital in a cross-sectional survey between May and August 2015 with the use of an anonymous, self-administered questionnaire interview.

RESULTS
Of the 1010 participants, 93.7% were receiving cART with the latest mean CD4 count and plasma HIV RNA load of 587 cells/mm(3) and 2.73 log10 copies/mL, respectively. Overall, 71.9% were willing to donate organs. In multivariate analysis, factors associated with willingness to donate organs included college or graduate school diploma (odds ratio [OR] 1.571, 95% confidence interval [CI] 1.166-2.191), registered willingness in the National Health Insurance system (OR 9.430, 95% CI 1.269-70.051), and knowledge of the information on HIV-positive deceased donors (HIVDD) (OR 1.673, 95% CI 1.073-2.608).

CONCLUSIONS
We concluded that a significant proportion (71.9%) of HIV-positive Taiwanese patients were willing to donate their organs. The willingness was associated with a higher education level, prior registered willingness to donate organs, and awareness of HIVDD. This article is protected by copyright. All rights reserved.

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