Does Splenomegaly Impact Transplant Outcomes?
Splenomegaly did not significantly impact transplant outcomes in patients who underwent hematopoietic stem cell transplantation for myelofibrosis.
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Showing 1 - 20 of 87 results for 'Splenomegaly'
Successful haploidentical hematopoietic stem cell transplantation (HSCT) and durable engraftment by repeated donor lymphocyte infusions for a Chinese patient with transfusion-dependent hemoglobin (Hb) Hammersmith and massive splenomegaly.
Hemoglobin (Hb) Hammersmith is a rare form of unstable β-chain hemoglobinopathy causing hemolytic anemia. This rare event led to a more serious transfusion-dependent phenotype in a patient. It was successfully cured by...
Read MoreGray Platelet Syndrome Presenting With Pancytopenia, Splenomegaly, and Bone Marrow Fibrosis.
Gray platelet syndrome (GPS) is a rare platelet storage pool disorder associated with a marked decrease or absence of platelet α-granules and their contents. It is characterized clinically by mild to moderate bleeding; moderate...
Read More![[Impact of splenomegaly on outcomes of allogeneic hematopoietic stem cell transplantation in patients with chronic myelomonocytic leukemia].](https://cdn.physiciansweekly.com/wp-content/uploads/2020/11/iStock-522519497.jpg)
[Impact of splenomegaly on outcomes of allogeneic hematopoietic stem cell transplantation in patients with chronic myelomonocytic leukemia].
To retrospectively analyzed the impact of splenomegaly on outcomes in patients with chronic...
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Endoscopic ultrasound-guided fine-needle aspiration for splenomegaly and focal splenic lesion: is it safe, effective and necessary?
splenomegaly and/or focal splenic lesions (FSL) have limited histopathologic studies due to the...
Read MoreHow Does Splenomagaly Impact Post-HCTs?
In a study published in the Journal of Clinical Oncology, researchers evaluated the impact of splenomegaly on post hematopoietic cell transplant (HCT) outcomes in patients with myelofibrosis using precise 3D volumetric...
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Anti-T-Lymphocyte Globulin Improves Survival Post-AlloHCT in Patients With Myelofibrosis
Anti-T-lymphocyte globulin significantly reduced the risk of GvHD, relapse, or death by 48%, enhancing GRFS, especially in matched donor transplants.
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Allogeneic HSCT for Myelofibrosis: What to Know as More Patients Receive Treatment
Authors of a recent review provide updates on stem cell transplants for myelofibrosis, with an emphasis on managing graft versus host disease and relapse.
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Transplantation Increasingly Considered in Older Patients With Comorbidities
T he selection process for transplant eligibility in myelofibrosis involves various factors such as age, dis – ease stage, comorbidities, performance status, and donor availability. Tools like the Myelofibrosis Transplant...
Read MorePrognostic factors of idiopathic hypereosinophilic syndrome: A nationwide survey in Japan.
Idiopathic hypereosinophilic syndrome (iHES) is a condition wherein persistent hypereosinophilia associated with end-organ damage occurs without any known causes. Due to the rarity of the disease, insufficient knowledge has been...
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US Emergency Medicine Physicians Must Become Proficient in Malaria Management
The following is a summary of “Malaria: A Focused Review for the Emergency Medicine...
Read MoreA Case of Non-cirrhotic Portal Hypertension With Antiphospholipid Syndrome.
Nodular regenerative hyperplasia (NRH) and obliterative portal venopathy (OPV) are two causes of non-cirrhotic portal hypertension (NCPH), which is a vascular liver disease wherein clinical signs of portal hypertension (PHT),...
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Exploring the Role of Splenic Irradiation for Myelofibrosis Before HCT
The following is a summary of “Splenic irradiation for myelofibrosis prior to hematopoietic...
Read MoreIschemic stroke as an initial performance of polycythemia vera in young adults: A case report and literature review.
As the second leading cause of death and disability worldwide, stroke is mainly caused by atherosclerosis and cardiac embolism, particularly in older individuals. Nevertheless, in young and otherwise healthy individuals, the...
Read MoreA rare case of esophageal variceal bleeding as a result of portal hypertension due to extra-hepatic portal vein obstruction and its management in a 7-year-old.
Extrahepatic Portal Vein Obstruction is the most common cause of portal hypertension in children. However, it has a very low prevalence. Esophageal varices due to portal hypertension in children can lead to recurrent episodes of...
Read MoreContrasting STX11 and SLP76 Gene Defects in an Inborn Error Immune Disorder
The following is a summary of “Opposing effects of two gene defects in STX11 and SLP76 on the disease in a patient with an inborn error of immunity,” published in the December 2023 issue of Allergy & Immunology...
Read MoreLeft-sided portal hypertension: Update and proposition of management algorithm.
Left-sided or segmental portal hypertension (SPHT) is a rare entity, most often associated with pancreatic disease or antecedent pancreatic surgery. The starting point is splenic vein obstruction secondary to local inflammation...
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Unveiling the Interplay of PIEZO1-TMEM16F in Hereditary Xerocytosis: Understanding and Targeting Pathways
The following is a summary of “Deciphering and Disrupting PIEZO1-TMEM16F Interplay in Hereditary...
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Efficacy and safety of 5-aminolevulinic acid in adult-onset Still’s disease: A preclinical study in mice and a pilot study in humans.
The study aimed to investigate the therapeutic effects of 5-aminolevulinic acid/sodium ferrous...
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