Skin involvement is common in systemic lupus erythematosus (SLE), but may be resistant to conventional treatment. We sought to evaluate the efficacy of anifrolumab (ANI) in refractory cutaneous manifestations of SLE.Case series...
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Depleting plasma cells with an anti-CD38 antibody led to ameliorations in multiple measures of systemic lupus erythematosus in an open-label phase 2 trial.
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The management of neuropsychiatric systemic lupus erythematosus (NPSLE) poses considerable...
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The U.S. Food and Drug Administration has approved a 200-mg subcutaneous route of administration...
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Patient Case A 33-year-old female patient has been diagnosed with Crohn’s disease and is...
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Systemic lupus erythematosus (SLE) poses formidable challenges due to its multifaceted etiology...
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A recent study investigating the role of the ceRNA mechanism in promoting systemic lupus...
Read MoreRecent studies on molecular pathways have elucidated novel therapeutic approaches in inflammatory and autoimmune skin disorders. Specifically, the dysregulation of the Janus kinase signal transducer and activator of...
Read MoreEnteritis is one of the rare systemic manifestations in childhood-onset systemic lupus erythematosus and its diagnosis is very challenging. This is a rare case of an adolescent girl with recurrent non-specific gastro-intestinal...
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Systemic lupus erythematosus (SLE) is a complex autoimmune disease with varying symptoms and multi-organ damage. Relapse-remission cycles often persist for many patients for years with the current treatment. Improved...
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The following is a summary of “Patient and physician perspectives of systemic lupus erythematosus...
Read MoreSystemic Lupus Erythematosus (SLE) is an autoimmune disorder characterized by autoantibody production and organ involvement. The role of toll-like receptor-7 in SLE is well established. Although genetic variations in the TLR-7...
Read MoreSystemic lupus erythematosus (SLE) associated macrophage activation syndrome (MAS) is clinically severe, with a high mortality rate and rare neuropsychiatric symptoms. In the course of diagnosis and treatment, it is necessary to...
Read MoreThis study aimed to investigate the frequency and features of diffuse alveolar hemorrhage (DAH) in Chinese patients with systemic lupus erythematosus (SLE) and evaluate the association of DAH with the features. A total of 943...
Read MoreTo estimate the direct healthcare cost progression from before to after systemic lupus erythematosus (SLE) diagnosis and to compare healthcare costs by disease severity.Patients with incident SLE diagnosed between 2008 and 2018...
Read MoreRetinal migraine is a diagnosis of exclusion and is characterized by repeated episodes of transient monocular blindness associated with migraine. We report a case of systemic lupus erythematosus with acute episodes mimicking...
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1. In this cross-sectional study, there was a significant negative correlation between anxiety...
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Environmental exposure may function as a contributing risk factor in the development of systemic...
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Neuromyelitis optica (NMO), also known as Devic’s disease, is a rare inflammatory...
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Sodium is vital for human health. High salt intake is a global health problem and is associated...
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