Rilzabrutinib is a covalent, reversible BTK inhibitor with multiple mechanisms targeting key immune thrombocytopenia (ITP) disease pathophysiology. The phase 3 LUNA3 study in previously treated adults with persistent/chronic ITP...
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Managing acute VTE risks in thrombocytopenia is challenging for clinicians, given the substantial gap in guidelines addressing the decision-making process.
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Findings showed high-dose, intensive steroid treatment was linked with both short- and long-term adverse events in patients with immune thrombocytopenia.
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Sovleplenib may offer QOL improvements for patients with primary immune thrombocytopenia.
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1. In this randomized controlled trial, CM313, an anti-CD38 monoclonal antibody therapy, was...
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Researchers tested if self-assessments could support the detection of smaller, but still critical, bleeding incidents in patients with immune thrombocytopenia.
Read MoreFcγ-receptors (FcγR) are membrane receptors expressed on a variety of immune cells, specialized in recognition of the Fc part of immunoglobulin G (IgG) antibodies. FcγRIIA-dependent platelet activation in platelet factor 4 (PF4)...
Read MoreSevere fever with thrombocytopenia syndrome (SFTS) is a serious infectious disease caused by the Dabie bandavirus, with a high mortality rate. Currently, there are no effective vaccines or specific treatments for SFTS. Early...
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The following is a summary of “Thrombocytopenia as a Bleeding Risk Factor in Atrial Fibrillation...
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FRIDAY, Oct. 6, 2023 (HealthDay News) — The first-in-class novel human immunoglobulin G1 Fc...
Read MoreIdentifying and monitoring adverse events following vaccination contributed to the safety and effectiveness of COVID-19 mass vaccination campaigns. In March 2021, international reports emerged of an adverse event following...
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Severe Fever with Thrombocytopenia Syndrome (SFTS) is an emerging infectious disease with...
Read MoreThe following is a summary of “Eltrombopag for Low-Risk Myelodysplastic Syndromes With Thrombocytopenia: Interim Results of a Phase II, Randomized, Placebo-Controlled Clinical Trial (EQOL-MDS),” published in the...
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Chronic immune thrombocytopenia purpura (ITP) in adults is a serious autoimmune disease in which...
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The following is a summary of “Interaction of thrombocytopenia, hemorrhage, and platelet...
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The following is a summary of “Efficacy and safety of eltrombopag in treating TKI-induced...
Read MoreThe following is a summary of the article “Platelet Transfusion before CVC Placement in Patients with Thrombocytopenia,” published in the May 2023 issue of Hematology by Baarle et al. Due to evidence gaps, there are...
Read MoreThrombosis with thrombocytopenia syndrome (TTS) is a very rare disorder described after vaccination with adenoviral vector-based COVID-19 vaccines. Co-occurring thrombosis with thrombocytopenia reported after vaccination can be...
Read MoreThe following is a summary of “Utility of indium-111 platelet scintigraphy for understanding the mechanism of thrombocytopenia associated with myelodysplastic syndromes and chronic myelomonocytic leukemia,” published...
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The following is a summary of “The role of CD8+ T-cell clones in immune...
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