Prior studies of inpatient rehabilitation of brain tumor patients demonstrate similar functional gains as compared to other rehabilitation populations. There are few studies specifically examining the rehabilitation of patients with glioblastoma.
To compare functional outcomes between matched patients admitted to acute inpatient rehabilitation after initial diagnosis of glioblastoma (iGBM) and after diagnosis of recurrent glioblastoma (rGBM).
We performed a retrospective, case-matched study using descriptive statistics to compare demographic information and functional outcomes as designated by the Functional Independence Measure (FIM) score.
A single, free-standing inpatient rehabilitation hospital.
Over a 20-mo period, twenty-five patients with iGBM were matched with 25 patients admitted to IRF with rGBM by the following criteria: 1) Side of lesion (left/right hemisphere), 2) Admission Total FIM score within 10 points, 3) Age within 10 yr, and 4) Sex. Nineteen of the 25 patients in each group were matched meeting all criteria, and 6 of the 25 patients were matched meeting three out of four criteria.
The primary outcome measures were differences in functional outcomes as measured by FIM scores.
There were no statistically significant differences (P < 0.05) between the groups in mean admission FIM scores, discharge FIM scores, FIM gains, and FIM efficiencies. There were no statistically significant differences in the development of complications during acute rehabilitation and transfer rate to acute care hospital. Sixty-four percent of patients in both groups were able to be discharged home.
This study demonstrated no statistically significant differences in functional outcomes between matched patients admitted with iGBM compared to rGBM. Further studies are indicated to examine the rehabilitation outcomes of patients with recurrent glioblastoma in inpatient rehabilitation.
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