The following is a summary of “Bladder Capacity in Women With Overactive Bladder Syndrome: A Cross-sectional Study,” published in the SEPTEMBER 2023 issue of Urology by Lavalle, et al.
For a study, researchers sought to assess bladder capacity in women with idiopathic overactive bladder syndrome (OAB) using a combination of methods, including bladder diary, cystomanometry, and uroflowmetry. A secondary objective was to examine the agreement between different measures of bladder capacity and explore the relationship between bladder capacity and urinary frequency in OAB patients.
It was an observational cross-sectional multicentric study that involved female patients diagnosed with idiopathic OAB. All participants underwent a urodynamic study and were required to complete a 3-day bladder diary (3dBD). Various parameters were employed to calculate bladder capacity, including maximum cystometric capacity (MCC), voided volume (VV) during uroflowmetry, maximum voided volume (VVmax), and average voided volume (VVmed) assessed through the 3dBD. Reproducibility analysis was conducted to evaluate the agreement among these different measures of bladder capacity, utilizing the intraclass correlation coefficient (ICC) and the weighted Kappa index. The study also examined bladder capacity parameters in relation to urinary frequency.
The study found that bladder capacity measures were reduced in this population, except VVmax. The correlation between different bladder capacity variables was poor (ICC and weighted Kappa index <0.4). A weak negative linear relationship was observed between 24-hour frequency and average VV (Pearson coefficient -0.344).
In women with OAB, both MCC and average VV were diminished. However, MCC did not correlate well with functional bladder volumes determined by voiding diary in this patient population. The study contributed to a better understanding of bladder capacity in OAB patients and the limitations of different measurement methods.