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A Novel Approach to Identifying Trajectories of Mobility Change in Older Adults.

A Novel Approach to Identifying Trajectories of Mobility Change in Older Adults.
Author Information (click to view)

Ward RE, Beauchamp MK, Latham NK, Leveille SG, Percac-Lima S, Kurlinski L, Ni P, Goldstein R, Jette AM, Bean JF,


Ward RE, Beauchamp MK, Latham NK, Leveille SG, Percac-Lima S, Kurlinski L, Ni P, Goldstein R, Jette AM, Bean JF, (click to view)

Ward RE, Beauchamp MK, Latham NK, Leveille SG, Percac-Lima S, Kurlinski L, Ni P, Goldstein R, Jette AM, Bean JF,

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PloS one 2016 12 2211(12) e0169003 doi 10.1371/journal.pone.0169003
Abstract
OBJECTIVES
To validate trajectories of late-life mobility change using a novel approach designed to overcome the constraints of modest sample size and few follow-up time points.

METHODS
Using clinical reasoning and distribution-based methodology, we identified trajectories of mobility change (Late Life Function and Disability Instrument) across 2 years in 391 participants age ≥65 years from a prospective cohort study designed to identify modifiable impairments predictive of mobility in late-life. We validated our approach using model fit indices and comparing baseline mobility-related factors between trajectories.

RESULTS
Model fit indices confirmed that the optimal number of trajectories were between 4 and 6. Mobility-related factors varied across trajectories with the most unfavorable values in poor mobility trajectories and the most favorable in high mobility trajectories. These factors included leg strength, trunk extension endurance, knee flexion range of motion, limb velocity, physical performance measures, and the number and prevalence of medical conditions including osteoarthritis and back pain.

CONCLUSIONS
Our findings support the validity of this approach and may facilitate the investigation of a broader scope of research questions within aging populations of varied sizes and traits.

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