This review identified prospective cohort studies in the general population which showed incidence (23 papers) and risk factors (37 papers) for fibromyalgia and chronic widespread pain. Median incidence of physician diagnosed fibromyalgia in the general population was 4.3 per 1000 person-years [range = 0.33-18.8] but 14.0 [1.2 – 32.7] if medical illness was present. Median incidence of chronic widespread pain was 12.5 per 1000 person-years [7.2-81.6] but 67 per 1000 person years [14.8 to 124] for those with pre-existing pain. Risk factors included various childhood difficulties, female sex (except with pre-existing medical disorders) , older/middle age, smoking, high BMI, alcohol abstinence and pre-existing medical disorders in adulthood. The strongest associations were with sleep disorders, headaches and other pains, depression and illness behaviour.These data suggest strongly that there are many aetiological routes into fibromyalgia and future research could be enhanced by studying the underlying mechanisms relating to these risk factors.
April 20, 2020
Risk of Permanent Hypoparathyroidism After Total Thyroidectomy for Benign Disease: A Nationwide Population-based Cohort Study From Sweden.
February 18, 2020
Prediction of Benefit from Checkpoint Inhibitors in Mismatch Repair Deficient Metastatic Colorectal Cancer: Role of Tumor Infiltrating Lymphocytes.
January 23, 2020
- ACC 2020The American College of Cardiology decided to cancel ACC.20/WCC due to COVID-19, which was scheduled to take place March 28-30 in Chicago. However, ACC.20/WCC Virtual Meeting continues to release cutting edge science and practice changing updates for cardiovascular professionals on demand and free through June 2020.