Prior research indicates an association between prenatal pet exposure and immunoglobulin E (IgE) trajectory through age 2. To determine if this association persists during ages 10-14, researchers assessed data on a cohort of 1,193 mother-child pairs in southeast Michigan. The study team found that the area under the curve for IgE levels during ages 10-14 was 28.8% lower in children with prenatal pet exposure when compared with those with no such exposure. Dog ownership, associated with a 26.7% lower IgE trajectory, was the main driver of this association, with cat ownership having no significant association with IgE trajectory. The findings support the “hygiene hypothesis,” said Jay Portnoy, MD—who was not involved in the study, in a statement—which is based on dogs being particular carriers of bacteria from outside into the home and resulting in a potential influence on a child’s microbiome early in develop. The hypothesis is supported by previous studies suggesting an association between dog ownership and reduced risk of eczema in children. Race/Ethnicity and delivery method affected the association between pet exposure and IgE reductions, with children of African-American mothers experiencing an 11.3% reduction versus a 33.6% reduction in other races and ethnicities, and children delivered via cesarean delivery experiencing a 46.2% lower IgE trajectory versus an 18.1% lower trajectory in children delivered vaginally.
October 6, 2019
October 21, 2020
September 19, 2019
- ACC 2020The American College of Cardiology decided to cancel ACC.20/WCC due to COVID-19, which was scheduled to take place March 28-30 in Chicago. However, ACC.20/WCC Virtual Meeting continues to release cutting edge science and practice changing updates for cardiovascular professionals on demand and free through June 2020.
- ENDO: 2020ENDO 2020 Annual Conference has been canceled due to COVID-19. Here are highlights of emerging data that has still been released. Keep an eye out for ENDO Online 2020, which will take place from June 8 to 22.
- CROI 2020Every year, CROI hosts some of the world's leading experts in HIV research, who come to present exciting new data and drive forward the field of HIV/AIDS research. This year, due to COVID-19, CROI held their meeting virtually.