Almost 50% of patients admitted to the hospi- tal for management of COVID-19 have at least one complication, according to a study published in The Lancet. Investigators conducted a pros- pective, multicenter study in 302 UK healthcare facilities to characterize the extent and effect of COVID-19 complications. A total of 80,388 adult patients with confirmed or highly sus- pected SARS-CoV-2 infection leading to COVID-19 were included in the study between January 17 and August 4, 2020 (mean age, 71.1; 56.0% men). Of the 73,197 patients admitted to the hospital for management of COVID-19, 49.7% had at least one complication. The like- lihood of having a complication was higher for men and for those older than 60 (aged ≥60: 54.5% and 48.2% for men and women, respec- tively; aged <60: 48.8% and 36.6%, respective- ly). The most frequent complications were re- nal, complex respiratory, and systemic (24.3%, 18.4%, and 16.3%, respectively); there were also reports of cardiovascular, neurological, and gastrointestinal or liver complications (12.3%, 4.3%, and 10.8%, respectively).