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Ambulatory blood pressure in relation to oxygen desaturation index as simultaneously assessed by nighttime finger pulse oximetry at home.

Ambulatory blood pressure in relation to oxygen desaturation index as simultaneously assessed by nighttime finger pulse oximetry at home.
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Chen Q, Cheng YB, Liu CY, Guo QH, Xu SK, Huang QF, Sheng CS, Shen M, Zhu YJ, Li Y, Wang JG,


Chen Q, Cheng YB, Liu CY, Guo QH, Xu SK, Huang QF, Sheng CS, Shen M, Zhu YJ, Li Y, Wang JG, (click to view)

Chen Q, Cheng YB, Liu CY, Guo QH, Xu SK, Huang QF, Sheng CS, Shen M, Zhu YJ, Li Y, Wang JG,

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Journal of clinical hypertension (Greenwich, Conn.) 2018 03 22() doi 10.1111/jch.13254
Abstract

We investigated the relationship between ambulatory blood pressure (BP) and oxygen desaturation index (ODI), while accounting for pulse rate and age. ODI was assessed by overnight finger pulse oximetry in 2342 participants on the day of ambulatory BP monitoring, and calculated as the number of desaturation episodes per sleeping hour. Both BP and pulse rate increased significantly (P ≤ .006) from normal (< 5 events/h) to mildly (5-14), moderately (15-30), and severely (≥ 30 events/h) elevated ODI. The association for BP was substantially attenuated by accounting for pulse rate (partial r² from .003-.012 to .002-.006). In adjusted analysis, the associations of 24-hour diastolic BP and 24-hour pulse rate with ODI were dependent on age (P ≤ .0001) and only significant in younger subjects (< 60 years, P ≤ .0001). In conclusion, the association between ambulatory BP and ODI was partially mediated by pulse rate, a measure of sympathetic activity, and was more prominent in younger subjects.

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