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An isolated outbreak of diphtheria in South Africa, 2015.

An isolated outbreak of diphtheria in South Africa, 2015.
Author Information (click to view)

Mahomed S, Archary M, Mutevedzi P, Mahabeer Y, Govender P, Ntshoe G, Kuhn W, Thomas J, Olowolagba A, Blumberg L, McCarthy K, Mlisana K, DU Plessis M, VON Gottberg A, Moodley P,


Mahomed S, Archary M, Mutevedzi P, Mahabeer Y, Govender P, Ntshoe G, Kuhn W, Thomas J, Olowolagba A, Blumberg L, McCarthy K, Mlisana K, DU Plessis M, VON Gottberg A, Moodley P, (click to view)

Mahomed S, Archary M, Mutevedzi P, Mahabeer Y, Govender P, Ntshoe G, Kuhn W, Thomas J, Olowolagba A, Blumberg L, McCarthy K, Mlisana K, DU Plessis M, VON Gottberg A, Moodley P,

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Epidemiology and infection 2017 05 08145(10) 2100-2108 doi 10.1017/S0950268817000851
Abstract

An outbreak of respiratory diphtheria occurred in two health districts in the province of KwaZulu-Natal in South Africa in 2015. A multidisciplinary outbreak response team was involved in the investigation and management of the outbreak. Fifteen cases of diphtheria were identified, with ages ranging from 4 to 41 years. Of the 12 cases that were under the age of 18 years, 9 (75%) were not fully immunized for diphtheria. The case fatality was 27%. Ninety-three household contacts, 981 school or work contacts and 595 healthcare worker contacts were identified and given prophylaxis against Corynebacterium diphtheriae infection. A targeted vaccination campaign for children aged 6-15 years was carried out at schools in the two districts. The outbreak highlighted the need to improve diphtheria vaccination coverage in the province and to investigate the feasibility of offering diphtheria vaccines to healthcare workers.

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