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An RBD-Fc mucosal vaccine provides variant-proof protection against SARS-CoV-2 in mice and hamsters.

May 19, 2025

REFERENCES & ADDITIONAL READING

PubMed

ABOUT THE EXPERTS

  • Yanjun Zhang

    State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

    Guangzhou National Laboratory, Bio-island, Guangzhou, China.

    Yan Wu

    State Key Laboratory of Virology and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Beijing, China.

    Meng-Qian Zhang

    State Key Laboratory of Medicinal Chemical Biology, TianjinKey Laboratory of Biosensing and Molecular Recognition,Frontiers Science Centre for New Organic Matter, ResearchCentre for Analytical Sciences, College of Chemistry, Nankai University, Tianjin, PR China.

    Haiyue Rao

    State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

    Zhaoyong Zhang

    State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

    Xiangyue He

    State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

    Yiwen Liang

    State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

    Raoqing Guo

    State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

    Yaochang Yuan

    State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

    Jing Sun

    State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

    Helen M E Duyvesteyn

    Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK.

    Elizabeth E Fry

    Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK.

    David I Stuart

    Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, The Wellcome Centre for Human Genetics, Oxford, UK.

    Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.

    Diamond Light Source Ltd, Harwell Science & Innovation Campus, Didcot, UK.

    Jingxian Zhao

    State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

    Guangzhou National Laboratory, Bio-island, Guangzhou, China.

    XiaoYan Pan

    State Key Laboratory of Virology and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Beijing, China. panxy@wh.iov.cn.

    Shu-Lin Liu

    State Key Laboratory of Medicinal Chemical Biology, TianjinKey Laboratory of Biosensing and Molecular Recognition,Frontiers Science Centre for New Organic Matter, ResearchCentre for Analytical Sciences, College of Chemistry, Nankai University, Tianjin, PR China. shulin.liu@nankai.edu.cn.

    Jincun Zhao

    State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. zhaojincun@gird.cn.

    Guangzhou National Laboratory, Bio-island, Guangzhou, China. zhaojincun@gird.cn.

    Jiandong Huo

    State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. huojiandong@gird.cn.

    Guangzhou National Laboratory, Bio-island, Guangzhou, China. huojiandong@gird.cn.

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