Few studies have compared the endocrine-specific results of parathyroidectomy (PTx) with those of concurrent parathyroidectomy and thyroidectomy (PTx + Tx).

Collaborative Endocrine Surgery Quality Improvement Program participants were 10,019 patients (2014–2019). Bivariate and multivariable techniques were used to examine the baseline features and short-term (≤30 days) results for patients receiving PTx + Tx versus PTx.

Patients receiving PTx + Tx had an increased risk of developing clinical hypoparathyroidism (6.7% vs. 0.5%, P< 0.001), recurrent laryngeal nerve transection (0.4% vs. 0.1%, P = 0.002), and hematoma requiring evacuation (1.0% vs 0.2%, P< 0.001). After PTx + Tx as opposed to PTx, readmissions and trips to the ED for hypocalcemia were more common. Odds Ratio (OR): 8.0, 95% CI: 5.7-11.1, P< 0.001; concurrent surgery was linked to an 8-fold increased risk of short-term problems.

Compared to individuals with parathyroidectomy alone, those who received PTx + Tx had higher rates of postoperative complications, ED visits, and readmissions. The results could assist in direct talks between a physician and a patient about the dangers of concurrent surgery.

Reference: americanjournalofsurgery.com/article/S0002-9610(22)00219-7/fulltext