This study was done to investigate the effects of severe preeclampsia on the RNFL, macula thickness, and ganglion cell density in pregnancy and postpartum, using HD-OCT.

28 stable pregnant patients were included in the study who were diagnosed with severe preeclampsia and the control group, and gestational week-matched healthy pregnant women. HD-OCT measurements were taken by the same researcher using a Cirrus HD-OCT device and were repeated at 2 months postpartum.

The mean systolic pressure, diastolic pressure, and IPP values measured in pregnancy were determined to be higher in the preeclampsia group than in the control group. The mean RNFL, macula thickness, ganglion cell analysis, and IOP values during pregnancy were determined to be similar in both groups. No significant difference was determined postpartum between the groups in respect of mean systolic pressure, diastolic pressure, RNFL, macula thickness, ganglion cell analysis, and IOP values. Mean IPP during pregnancy was higher than the mean postpartum IPP in the severe pre-eclampsia group.

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This study evaluated ganglion cell density of the retina, macula thickness, and RNFL using HD-OCT in severe pre-eclampsia cases, both during pregnancy and postpartum.

Reference: https://www.tandfonline.com/doi/full/10.1080/10641955.2020.1758938