Research has shown that women who are treated with chest radiation for a pediatric malignancy have a significantly increased risk of developing breast cancer at a young age. The risk of breast cancer is greatest among female pediatric cancer survivors who have been treated for Hodgkin lymphoma with high-dose mantle radiation. By age 45, it is estimated that 12% to 20% of women treated with moderate-to-high dose chest radiation will be diagnosed with breast cancer. For perspective, women with a BRCA gene mutation have an estimated cumulative incidence of breast cancer that ranges from 1% to 5% at age 30 and from 10% to 19% at age 40.
Ubiquitin-specific protease 14 regulates ovarian cancer cisplatin-resistance by stabilizing BCL6 oncoprotein.
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- AACR-2020The American Association for Cancer Research is the world's oldest and largest professional association related to cancer research.
- ACC 2020The American College of Cardiology decided to cancel ACC.20/WCC due to COVID-19, which was scheduled to take place March 28-30 in Chicago. However, ACC.20/WCC Virtual Meeting continues to release cutting edge science and practice changing updates for cardiovascular professionals on demand and free through June 2020.