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Association between air pollution and rhinitis incidence in two European cohorts.

Association between air pollution and rhinitis incidence in two European cohorts.
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Burte E, Leynaert B, Bono R, Brunekreef B, Bousquet J, Carsin AE, De Hoogh K, Forsberg B, Gormand F, Heinrich J, Just J, Marcon A, Künzli N, Nieuwenhuijsen M, Pin I, Stempfelet M, Sunyer J, Villani S, Siroux V, Jarvis D, Nadif R, Jacquemin B,


Burte E, Leynaert B, Bono R, Brunekreef B, Bousquet J, Carsin AE, De Hoogh K, Forsberg B, Gormand F, Heinrich J, Just J, Marcon A, Künzli N, Nieuwenhuijsen M, Pin I, Stempfelet M, Sunyer J, Villani S, Siroux V, Jarvis D, Nadif R, Jacquemin B, (click to view)

Burte E, Leynaert B, Bono R, Brunekreef B, Bousquet J, Carsin AE, De Hoogh K, Forsberg B, Gormand F, Heinrich J, Just J, Marcon A, Künzli N, Nieuwenhuijsen M, Pin I, Stempfelet M, Sunyer J, Villani S, Siroux V, Jarvis D, Nadif R, Jacquemin B,

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Environment international 2018 03 29115() 257-266 pii S0160-4120(17)31974-8
Abstract
BACKGROUND
The association between air pollution and rhinitis is not well established.

AIM
The aim of this longitudinal analysis was to study the association between modeled air pollution at the subjects’ home addresses and self-reported incidence of rhinitis.

METHODS
We used data from 1533 adults from two multicentre cohorts’ studies (EGEA and ECRHS). Rhinitis incidence was defined as reporting rhinitis at the second follow-up (2011 to 2013) but not at the first follow-up (2000 to 2007). Annual exposure to NO, PMand PMat the participants’ home addresses was estimated using land-use regression models developed by the ESCAPE project for the 2009-2010 period. Incidence rate ratios (IRR) were computed using Poisson regression. Pooled analysis, analyses by city and meta-regression testing for heterogeneity were carried out.

RESULTS
No association between long-term air pollution exposure and incidence of rhinitis was found (adjusted IRR (aIRR) for an increase of 10 μg·mof NO1.00 [0.91-1.09], for an increase of 5 μg·mof PM: 0.88 [0.73-1.04]). Similar results were found in the two-pollutant model (aIRR for an increase of 10 μg·mof NO1.01 [0.87-1.17], for an increase of 5 μg·mof PM: 0.87 [0.68-1.08]). Results differed depending on the city, but no regional pattern emerged for any of the pollutants.

CONCLUSIONS
This study did not find any consistent evidence of an association between long-term air pollution and incident rhinitis.

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