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Association between modified CHA2DS2-VASc Score with Ankle-Brachial index < 0.9.

Association between modified CHA2DS2-VASc Score with Ankle-Brachial index 
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Hsu PC, Lee WH, Lee HC, Tsai WC, Chu CY, Chen YC, Lee CS, Lin TH, Voon WC, Sheu SH, Su HM,


Hsu PC, Lee WH, Lee HC, Tsai WC, Chu CY, Chen YC, Lee CS, Lin TH, Voon WC, Sheu SH, Su HM, (click to view)

Hsu PC, Lee WH, Lee HC, Tsai WC, Chu CY, Chen YC, Lee CS, Lin TH, Voon WC, Sheu SH, Su HM,

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Scientific reports 2018 01 198(1) 1175 doi 10.1038/s41598-018-19243-y
Abstract

The ankle-brachial index (ABI) is a reliable diagnostic examination for peripheral arterial occlusive disease (PAOD). We previously reported CHADS2 score was significantly correlated with PAOD. However, the association between CHA2DS2-VASc score and ABI < 0.9 is not evaluated in the literature. The aim of the present study was to investigate whether CHA2DS2-VASc score has a strong association with PAOD. We enrolled 1482 patients in this study. PAOD was defined as ABI < 0.9 in either leg. Vascular disease in CHA2DS2-VASc score was modified as vascular disease except PAOD. Of the 1482 subjects, the prevalence of ABI < 0.9 was 5.6%. Multivariate analysis showed that the increased age, decreased estimated glomerular filtration rate and increased modified CHA2DS2-VASc score (OR, 1.764; p < 0.001) were independent associated with ABI < 0.9. In addition, the percentage of ABI < 0.9 in patients with modified CHA2DS2-VASc score of 0, 1, and <2 were 0%, 0.9%, and 0.7%, respectively (All < 1%). Our study demonstrated modified CHA2DS2-VASc score was significantly associated with ABI < 0.9. Calculation of modified CHA2DS2-VASc score might be useful in identifying patients with PAOD and in stratifying the risk of PAOD in non-AF patients.

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