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Association between radioiodine treatment for thyroid cancer and risk of stroke.

Association between radioiodine treatment for thyroid cancer and risk of stroke.
Author Information (click to view)

Lin CY, Lin CL, Lo YC, Kao CH,


Lin CY, Lin CL, Lo YC, Kao CH, (click to view)

Lin CY, Lin CL, Lo YC, Kao CH,

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Head & neck 2017 08 1639(11) 2311-2318 doi 10.1002/hed.24903

Abstract
BACKGROUND
The purpose of this study was to evaluate the association between radioiodine (I-131) therapy for thyroid cancer and the risk of stroke in Taiwan.

METHODS
A total of 10 104 of the patients aged 20 years or older, who were newly diagnosed with thyroid cancer during 2000-2010, were recruited and classified into 2 cohorts according to whether they received I-131 therapy through 1:1 propensity score matching. The cumulative Kaplan-Meier curves for the incidence of stroke in the 2 cohorts were compared using the log-rank test.

RESULTS
After adjustment for age, sex, and comorbidities, the I-131 therapy group showed no significantly higher risk of ischemic stroke (adjusted HR [aHR] = 1.05; 95% confidence interval [CI] = 0.82-1.34) or hemorrhagic stroke (aHR = 1.06; 95% CI = 0.58-1.93) than did the non-I-131 therapy group.

CONCLUSION
The I-131 treatment for thyroid cancer did not increase the risk of stroke during 10-year follow-up.

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