Here are what the editors at HealthDay consider to be the most important developments in Cardiology for August 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Cerebrovascular Risk Factors May Up Risk for Parkinson Disease
FRIDAY, Aug. 30, 2019 (HealthDay News) — Most cerebrovascular risk factors are associated with an increased risk for subsequent diagnosis of Parkinson disease, according to a study published online Aug. 29 in the Annals of Neurology.
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FDA: Risk From Tainted Blood Pressure Drugs Very Low
THURSDAY, Aug. 29, 2019 (HealthDay News) — The health risk from contamination of widely used generic blood pressure medications, angiotensin II receptor blockers, is very low, according to the U.S. Food and Drug Administration.
AP News Article
More Information: FDA
Cancer Survivors Face Long-Term Cardiovascular Risk
THURSDAY, Aug. 29, 2019 (HealthDay News) — Cancer survivors face an increase in the long-term risk for cardiovascular disease, according to a study published online Aug. 20 in The Lancet.
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High-Intensity Training Improves Walking in Stroke Survivors
THURSDAY, Aug. 29, 2019 (HealthDay News) — High-intensity stepping training that mimics real-world conditions may better improve walking ability in stroke survivors, according to a study published in the September issue of Stroke.
Low Nurse and Support Staffing Tied to Higher Inpatient Mortality
WEDNESDAY, Aug. 28, 2019 (HealthDay News) — Low levels of nurse and nursing support staffing are associated with increased inpatient mortality, according to a study published online Aug. 7 in BMJ Quality & Safety.
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Central Obesity Tied to CAD in Postmenopausal Chest Pain
WEDNESDAY, Aug. 28, 2019 (HealthDay News) — For postmenopausal women with stable chest pain, central obesity, but not overall obesity, is associated with obstructive coronary artery disease (CAD), according to a study published online Aug. 28 in Menopause.
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Decline in Mortality Rates for Cardiometabolic Disease Slowing
TUESDAY, Aug. 27, 2019 (HealthDay News) — Age-adjusted mortality rates (AAMRs) for cardiometabolic diseases are continuing to decline but at a slower rate, according to a research letter published online Aug. 27 in the Journal of the American Medical Association.
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LV Hypertrophy Predicts Long-Term Risk for CV Events
TUESDAY, Aug. 27, 2019 (HealthDay News) — Elevated left ventricular (LV) mass is associated with an increased long-term risk for cardiovascular (CV) events, according to a study published online Aug. 27 in Radiology.
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Psoriasis Independently Linked to Increased Mortality Risk
TUESDAY, Aug. 27, 2019 (HealthDay News) — Psoriasis is significantly associated with an increased mortality risk, according to a study published online Aug. 12 in the Journal of the American Academy of Dermatology.
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CT Scan Screen for Lung Cancer Can ID Smoking-Related Diseases
TUESDAY, Aug. 27, 2019 (HealthDay News) — Lung cancer screening (LCS) computed tomography (CT) scans can be used to identify smoking-related conditions that frequently are associated with adverse events, according to a study published in the July issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation.
Artificial Intelligence Can Predict Patient Gender, Age From ECG
TUESDAY, Aug. 27, 2019 (HealthDay News) — Patient gender and age can be predicted by applying artificial intelligence (AI) to an electrocardiogram (ECG), according to a study published online Aug. 27 in Circulation: Arrhythmia and Electrophysiology.
Smaller + Larger Infarctions May Escalate Later Cognitive Decline
TUESDAY, Aug. 27, 2019 (HealthDay News) — The combination of smaller and larger infarctions detected in stroke-free individuals in middle age is associated with substantial cognitive decline later in life, according to a study published online Aug. 27 in the Annals of Internal Medicine.
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Risk for Cardiovascular Disease Greater for Childhood Cancer Survivors
MONDAY, Aug. 26, 2019 (HealthDay News) — Survivors of childhood cancer have an increased risk for all subtypes of cardiovascular disease (CVD), according to a research letter published online Aug. 26 in Circulation.
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In-Store E-Cigarette Marketing Influences Use in Young People
MONDAY, Aug. 26, 2019 (HealthDay News) — Recall of electronic nicotine delivery systems (ENDS) marketing at retail stores is associated with increased subsequent ENDS initiation among youth and young adults, according to a study published online Aug. 26 in Pediatrics.
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Aerobic Exercise Programs Benefit Stroke Survivors
MONDAY, Aug. 26, 2019 (HealthDay News) — Group-based aerobic exercise programs, like cardiac rehabilitation, provide benefits to stroke survivors, according to a review published online Aug. 14 in the Journal of the American Heart Association.
Poor HIV Control Ups Risk for Sudden Cardiac Death in Heart Failure
FRIDAY, Aug. 23, 2019 (HealthDay News) — Persons living with HIV (PHIV) who are hospitalized with heart failure are at an increased risk for subsequent sudden cardiac death (SCD), according to a study published online Aug. 7 in JACC: Heart Failure.
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Prurigo Nodularis Associated With Mental Health Disorders
FRIDAY, Aug. 23, 2019 (HealthDay News) — Prurigo nodularis (PN) is associated with mental health disorders, systemic illnesses, and HIV infection, according to a study published online Aug. 15 in the Journal of Investigative Dermatology.
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Low-Cost, Fixed-Dose Polypill Reduces Risk for Major CV Events
FRIDAY, Aug. 23, 2019 (HealthDay News) — Use of a four-component polypill can effectively reduce the risk for major cardiovascular events, according to a study published in the Aug. 24 issue of The Lancet.
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Rx Size Predicts Persistent Opioid Use After Cardiothoracic Surgery
THURSDAY, Aug. 22, 2019 (HealthDay News) — Prescription size is associated with increased new persistent opioid use among patients after cardiothoracic surgery, according to a study published online Aug. 22 in the Annals of Thoracic Surgery.
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More Physical Activity at Any Intensity May Reduce Mortality
THURSDAY, Aug. 22, 2019 (HealthDay News) — For middle-aged and older adults, more physical activity at any intensity and less sedentary time are associated with a reduced risk for premature mortality, according to a review published online Aug. 21 in The BMJ.
Type 2 Diabetes Associated With Poorer Outcomes in Heart Failure
THURSDAY, Aug. 22, 2019 (HealthDay News) — For patients with heart failure, type 2 diabetes is associated with structural changes in the heart, poorer quality of life, and increased mortality, according to a study published online Aug. 21 in the Journal of the American Heart Association.
Intensifying BP Meds at Hospital Discharge May Harm Elderly
THURSDAY, Aug. 22, 2019 (HealthDay News) — Increasing blood pressure medications at hospital discharge for elderly patients hospitalized with noncardiac conditions does not improve long-term outcomes and is tied to short-term harms, according to a study published online Aug. 19 in JAMA Internal Medicine.
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Short-Term Exposure to PM10 and PM2.5 Affects Mortality
WEDNESDAY, Aug. 21, 2019 (HealthDay News) — Short-term exposure to inhalable particulate matter (PM) with an aerodynamic diameter of 10 µm or less (PM10) and fine PM (PM2.5) is positively associated with daily all-cause, cardiovascular, and respiratory mortality in more than 600 cities, according to a study published in the Aug. 22 issue of the New England Journal of Medicine.
Serelaxin Does Not Lower CV Death in Acute Heart Failure
WEDNESDAY, Aug. 21, 2019 (HealthDay News) — An infusion of serelaxin does not result in a lower incidence of death from cardiovascular causes or worsening of heart failure among patients hospitalized for acute heart failure, according to a study published in the Aug. 22 issue of the New England Journal of Medicine.
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Taking Buprenorphine for Opioid Use Disorder May Up Other Med Compliance
WEDNESDAY, Aug. 21, 2019 (HealthDay News) — Using buprenorphine to treat opioid use disorder (OUD) may increase adherence to treatments for other chronic conditions, according to a study published in the September issue of Medical Care.
High, Increasing BP in Midlife Tied to Brain Changes in Late Life
WEDNESDAY, Aug. 21, 2019 (HealthDay News) — There appears to be a correlation for high and increasing blood pressure (BP) from early adulthood and into midlife with white matter hyperintensity volume (WMHV) and smaller brain volumes at age 69 to 71 years, according to a study published online Aug. 21 in The Lancet Neurology.
Quitting Smoking Linked to Lower CVD Risk Within Five Years
WEDNESDAY, Aug. 21, 2019 (HealthDay News) — Quitting smoking is associated with reduced rates of incident cardiovascular disease (CVD) within five years compared with current smoking, although the risks remain elevated after five years compared with never smoking, according to a study published in the Aug. 20 issue of the Journal of the American Medical Association.
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Editor’s Note
Association for Diabetes, Stroke Risk Varies by Age, Race, Sex
TUESDAY, Aug. 20, 2019 (HealthDay News) — The magnitude of the association of diabetes with stroke risk varies by age, race, and sex, according to a study published online Aug. 7 in Diabetes Care.
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MRI Shows Vaping Has Transient Impact on Vascular Function
TUESDAY, Aug. 20, 2019 (HealthDay News) — In healthy nonsmokers, inhaling nicotine-free electronic cigarette aerosol has a transient impact on endothelial function, according to a study published online Aug. 20 in Radiology.
BP Outside of Clinic May Better Predict Outcomes in Black Patients
MONDAY, Aug. 19, 2019 (HealthDay News) — Among African-Americans, higher daytime and nighttime systolic blood pressure (SBP) is associated with an increased risk for cardiovascular disease (CVD) events and all-cause mortality independent of blood pressure (BP) levels measured in the clinic, according to a study published online Aug. 14 in JAMA Cardiology.
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Genetic Liability to Insomnia Linked to Increased Odds of CVDs
MONDAY, Aug. 19, 2019 (HealthDay News) — Genetic liability to insomnia is associated with increased odds of major cardiovascular diseases, according to a research letter published online Aug. 19 in Circulation.
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AHA: Prescription Omega-3 Fatty Acids Effectively Lower Triglycerides
MONDAY, Aug. 19, 2019 (HealthDay News) — After any underlying causes are addressed and diet and lifestyle strategies are implemented, prescription omega-3 fatty acids (n-3 FAs), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) or EPA only, at a dose of 4 g/day are effective for lowering triglycerides as monotherapy or in combination with other agents, according to an American Heart Association science advisory published online Aug. 19 in Circulation.
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Recommendations Developed for Management of Lyme Disease
FRIDAY, Aug. 16, 2019 (HealthDay News) — The Infectious Diseases Society of America, the American Academy of Neurology, and the American College of Rheumatology have released a draft of their joint clinical practice guidelines for the management of Lyme disease.
Draft Guidelines
Draft Supplemental Materials
Comment on Guidelines
Intensive BP Therapy Not Beneficial in Nursing Home Residents
FRIDAY, Aug. 16, 2019 (HealthDay News) — Long-term nursing home residents with hypertension do not experience significant benefits from more intensive antihypertensive treatment, according to a study published online July 22 in the Journal of the American Geriatrics Society.
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Advertising Can Promote Interest in Health-Related Research
THURSDAY, Aug. 15, 2019 (HealthDay News) — Advertising current local health-related research using large TV monitors in emergency department waiting rooms can increase the short-term interest in health-related research, according to a study published online Aug. 1 in BMJ Open.
FDA Proposes Graphic Warning Labels on Cigarettes
THURSDAY, Aug. 15, 2019 (HealthDay News) — Smokers would have to get past some gruesome imagery to purchase a pack of cigarettes under a new rule proposed Thursday by the U.S. Food and Drug Administration.
Nonpersistence, Low Adherence to BP Meds Common in Under 65s
THURSDAY, Aug. 15, 2019 (HealthDay News) — Nonpersistence and low adherence are common among younger adults initiating antihypertensive medications and have not improved over time, according to a study published in the July issue of Hypertension.
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CDC: Prescription Drug Use Similar in United States, Canada
WEDNESDAY, Aug. 14, 2019 (HealthDay News) — Use of prescription drugs is similar in the United States and Canada, with almost 70 percent of adults aged 40 to 79 years using at least one prescription drug, according to an August data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.
Antiarrhythmic Drugs May Up Fall Injuries in Older A-Fib Patients
WEDNESDAY, Aug. 14, 2019 (HealthDay News) — Use of antiarrhythmic drugs (AADs) is associated with a higher risk for fall-related injuries and syncope among older patients with atrial fibrillation (AF), according to a study published online July 24 in the Journal of the American Geriatrics Society.
Low Muscle Mass in the Arms, Legs Tied to Mortality in Elderly
WEDNESDAY, Aug. 14, 2019 (HealthDay News) — Low muscle mass is associated with all-cause and cardiovascular mortality risk in the elderly, according to a study published in the July issue of the Journal of Bone and Mineral Research.
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Non-Hospital-Based Provider-to-Patient Telehealth Use Growing
TUESDAY, Aug. 13, 2019 (HealthDay News) — Use of non-hospital-based provider-to-patient telehealth grew almost 1,400-fold from 2014 to 2018, according to a FAIR Health White Paper.
BP From Midlife to Late Life Tied to Risk for Subsequent Dementia
TUESDAY, Aug. 13, 2019 (HealthDay News) — The risk for subsequent dementia is significantly increased for blood pressure patterns of midlife and late-life hypertension as well as midlife hypertension and late-life hypotension; and intensive blood pressure treatment is associated with a smaller increase in cerebral white matter lesion volume, according to two studies published in the Aug. 13 issue of the Journal of the American Medical Association.
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Comorbid CVD May Up Mortality With ADT for Prostate Cancer
TUESDAY, Aug. 13, 2019 (HealthDay News) — Elderly prostate cancer patients with preexisting cardiovascular diseases (CVDs) using abiraterone acetate (AA) or enzalutamide (ENZ) have higher short-term mortality compared with their counterparts without CVDs, according to a study published online Aug. 13 in European Urology.
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CVD Mortality Declines Are Slowing in High-Income Countries
TUESDAY, Aug. 13, 2019 (HealthDay News) — High-income countries have experienced a recent slowing in the cardiovascular disease (CVD) mortality decline, according to a study published online Aug. 5 in the International Journal of Epidemiology.
General, Abdominal Adiposity Linked to Mortality in Mexicans
TUESDAY, Aug. 13, 2019 (HealthDay News) — General and abdominal adiposity are associated with mortality in a population of Mexican adults, according to a study published online Aug. 13 in the Annals of Internal Medicine.
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One-Third of Physicians Will Take 10+ Years to Pay Off Debt
MONDAY, Aug. 12, 2019 (HealthDay News) — Nearly two-thirds of actively practicing physicians are still carrying medical school debt, according to the Medical School Debt Report 2019, published by the staffing firm Weatherby Healthcare.
Medical School Debt Report 2019
Flu Vaccine Tied to Better Long-Term Outcomes in Elderly ICU Survivors
MONDAY, Aug. 12, 2019 (HealthDay News) — Among elderly patients, influenza vaccination is associated with a reduced risk for dying in the year following discharge from an intensive care unit (ICU), according to a study published in the July issue of Intensive Care Medicine.
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Perfusion Assessment Key for Critical Limb Ischemia Diagnosis
MONDAY, Aug. 12, 2019 (HealthDay News) — Strategies for perfusion assessment necessary for critical limb ischemia (CLI) diagnosis remain limited, according to an American Heart Association scientific statement published online Aug. 12 in Circulation.
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Better CV Health in Midlife Tied to Reduced Dementia Risk Later
THURSDAY, Aug. 8, 2019 (HealthDay News) — Adherence to the Life Simple 7 ideal cardiovascular health recommendations in midlife is associated with reduced incidence of dementia later in life, according to a study published online Aug. 7 in The BMJ.
Persistent Inflammation After Sepsis Linked to Higher Mortality
THURSDAY, Aug. 8, 2019 (HealthDay News) — About two-thirds of patients who survive hospitalization for sepsis have persistent elevation of inflammation and immunosuppression biomarkers, which is linked to increased mortality, according to a study published online Aug. 7 in JAMA Network Open.
NSAIDs Contribute to Increased CVD Risk in Osteoarthritis
THURSDAY, Aug. 8, 2019 (HealthDay News) — Osteoarthritis (OA) is an independent risk factor for increased cardiovascular disease (CVD), and nonsteroidal anti-inflammatory drugs (NSAIDs) contribute substantially to this risk, according to a study published online Aug. 6 in Arthritis & Rheumatology.
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Strong SSRI May Be Tied to Small Decrease in Ischemic Stroke Risk
WEDNESDAY, Aug. 7, 2019 (HealthDay News) — Antidepressants strongly inhibiting serotonin reuptake may be associated with a small reduction in the rate of ischemic stroke compared with weak reuptake inhibitors, according to a study published online Aug. 7 in Neurology.
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Medicare Spending on Essential Medicines Up 116 Percent From 2011 to 2015
WEDNESDAY, Aug. 7, 2019 (HealthDay News) — Spending associated with essential medicines grew substantially from 2011 to 2015 for Medicare Part D beneficiaries, according to a study published online July 17 in The BMJ.
At-Home Support Helps Stroke Patients Adjust After Hospitalization
WEDNESDAY, Aug. 7, 2019 (HealthDay News) — Stroke patients discharged with a case manager and access to an educational website reported significantly greater improvements in physical health after three months compared with those who had traditional care, according to a study published in the July issue of Circulation: Cardiovascular Quality and Outcomes.
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Recommendations Developed for Obesity Hypoventilation Syndrome
WEDNESDAY, Aug. 7, 2019 (HealthDay News) — In an official American Thoracic Society clinical practice guideline, published in the Aug. 1 issue of the American Journal of Respiratory and Critical Care Medicine, recommendations are presented to guide management and improve outcomes for patients with obesity hypoventilation syndrome (OHS).
Plant-Based Diets May Lower CV Disease, Deaths in Middle-Aged
WEDNESDAY, Aug. 7, 2019 (HealthDay News) — Diets higher in plant-based foods and lower in animal-based foods are associated with lower risks for developing or dying from cardiovascular disease among middle-aged adults, according to a study published online Aug. 7 in the Journal of the American Heart Association.
High-Intensity Lipid Lowering May Aid Very Elderly After ACS
TUESDAY, Aug. 6, 2019 (HealthDay News) — Among patients hospitalized for acute coronary syndrome (ACS), the greatest benefit from simvastatin-ezetimibe compared with simvastatin alone to lower lipid levels was observed in those 75 years of age or older, according to a study published online July 17 in JAMA Cardiology.
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Transdermal Optical Imaging Shows Promise for Measuring BP
TUESDAY, Aug. 6, 2019 (HealthDay News) — Transdermal optical imaging can be used to predict systolic, diastolic, and pulse pressure from facial blood flow data, according to a study published online Aug. 6 in Circulation: Cardiovascular Imaging.
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Low Specificity Limits Use of Focused Cardiac Ultrasonography
TUESDAY, Aug. 6, 2019 (HealthDay News) — Incorporating focused cardiac ultrasonography (FoCUS) into clinical examination has greater sensitivity, but not greater specificity, than clinical assessment alone for identifying left ventricular dysfunction and aortic or mitral valve disease, according to a review published Aug. 6 in the Annals of Internal Medicine.
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Lifestyle Counseling Frequency, CV Outcomes Linked in Diabetes
TUESDAY, Aug. 6, 2019 (HealthDay News) — For hyperglycemic adults with diabetes, a higher frequency of lifestyle counseling is associated with a lower incidence of a composite outcome of death and cardiovascular events, according to a study published online Aug. 1 in Diabetes Care.
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Electric Fans Help in Hot, Humid Conditions but Not Hot, Dry Ones
MONDAY, Aug. 5, 2019 (HealthDay News) — Electric fans reduce core temperature and cardiovascular strain and improve thermal comfort in hot, humid conditions but are detrimental for all measures in very hot, dry conditions, according to a research letter published online Aug. 6 in the Annals of Internal Medicine.
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BP, Waist Circumference, Lipids Should Be Measured Regularly
MONDAY, Aug. 5, 2019 (HealthDay News) — Blood pressure, waist circumference, fasting lipid profile, and blood glucose should be measured regularly to identify atherosclerotic cardiovascular disease (ASCVD) and type 2 diabetes mellitus (T2DM), according to guidelines published online July 31 in the Journal of Clinical Endocrinology & Metabolism.
Risk for Cardiovascular Deaths Increased With Hip, Knee OA
MONDAY, Aug. 5, 2019 (HealthDay News) — The risk for cardiovascular deaths is increased among patients with knee and hip osteoarthritis, according to a study published in the June issue of Osteoarthritis & Cartilage.
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Guidance Issued for Research Use of Cardiac MRI After MI
MONDAY, Aug. 5, 2019 (HealthDay News) — In a scientific expert panel consensus document, published in the July 16 issue of the Journal of the American College of Cardiology, recommendations are presented for how cardiac magnetic resonance (CMR) imaging after myocardial infarction (MI) is used in clinical research.
Estrogen Preps Differ in Effects on Heart Fat Deposits
FRIDAY, Aug. 2, 2019 (HealthDay News) — Hormone therapy formulations have differential effects on heart fat deposits in early menopausal women, according to a study published online Aug. 1 in the Journal of the American Heart Association.
Discontinuing Statins Linked to Cardiac Admissions in Elderly
FRIDAY, Aug. 2, 2019 (HealthDay News) — For elderly patients taking statins for primary prevention, statin discontinuation is associated with an increased risk for admission for any cardiovascular event, according to a study published online July 30 in the European Heart Journal.
Brand-Brand Competition Has Not Cut Prices in Pharma Market
FRIDAY, Aug. 2, 2019 (HealthDay News) — Brand-brand competition in the U.S. pharmaceutical market has not lowered drug list prices, according to a review published online July 30 in PLOS Medicine.
AI-Enabled ECG During Normal Sinus Rhythm Identifies A-Fib
FRIDAY, Aug. 2, 2019 (HealthDay News) — An artificial intelligence (AI)-enabled electrocardiograph (ECG) acquired during normal sinus rhythm can identify individuals with atrial fibrillation, according to a study published online Aug. 1 in The Lancet.
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Trump Admin Announces Plan to Allow Drug Imports From Canada
THURSDAY, Aug. 1, 2019 (HealthDay News) — Americans could import less expensive prescription drugs from Canada under a plan being developed by the Trump administration.
HHS Press Release
PhRMA Statement
Many Hospitals Lack Sufficient Surgery Volumes
THURSDAY, Aug. 1, 2019 (HealthDay News) — Patients can achieve better outcomes by choosing a hospital and a surgeon with adequate, ongoing experience performing a specific surgery, according to a new report entitled Safety In Numbers: The Leapfrog Group’s Report on High-Risk Surgeries Performed at American Hospitals.
Childhood BMI, HDL-C Variability May Up Later-Life Diabetes Risk
THURSDAY, Aug. 1, 2019 (HealthDay News) — High variability in body mass index (BMI) and high-density lipoprotein cholesterol (HDL-C) during childhood are associated with an increased risk for later-life diabetes, according to a study published online July 18 in Diabetes Care.
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