Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for August 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.
Cerebrovascular Risk Factors May Up Risk for Parkinson Disease
FRIDAY, Aug. 30, 2019 (HealthDay News) — Most cerebrovascular risk factors are associated with an increased risk for subsequent diagnosis of Parkinson disease, according to a study published online Aug. 29 in the Annals of Neurology.
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Dipeptidyl Peptidase-4 Inhibitors May Up Pancreatic Disease Risk
WEDNESDAY, Aug. 28, 2019 (HealthDay News) — Use of dipeptidyl peptidase-4 inhibitors (DPP-4i) is associated with increased risks for pancreatitis and pancreatic cancer in patients with newly diagnosed type 2 diabetes, according to a study published online Aug. 20 in Diabetes Care.
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Decline in Mortality Rates for Cardiometabolic Disease Slowing
TUESDAY, Aug. 27, 2019 (HealthDay News) — Age-adjusted mortality rates (AAMRs) for cardiometabolic diseases are continuing to decline but at a slower rate, according to a research letter published online Aug. 27 in the Journal of the American Medical Association.
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Psoriasis Independently Linked to Increased Mortality Risk
TUESDAY, Aug. 27, 2019 (HealthDay News) — Psoriasis is significantly associated with an increased mortality risk, according to a study published online Aug. 12 in the Journal of the American Academy of Dermatology.
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CT Scan Screen for Lung Cancer Can ID Smoking-Related Diseases
TUESDAY, Aug. 27, 2019 (HealthDay News) — Lung cancer screening (LCS) computed tomography (CT) scans can be used to identify smoking-related conditions that frequently are associated with adverse events, according to a study published in the July issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation.
Polyunsaturated Fatty Acids Have Little, No Impact on Diabetes
TUESDAY, Aug. 27, 2019 (HealthDay News) — Polyunsaturated fatty acids (PUFA) have little to no effect on the prevention or treatment of type 2 diabetes mellitus, according to a review published online Aug. 21 in The BMJ.
Liraglutide Ups Risk for Gallbladder, Biliary Tract Events
MONDAY, Aug. 26, 2019 (HealthDay News) — There is an increased risk for gallbladder- or biliary tract-related events among patients with type 2 diabetes taking liraglutide versus placebo, according to a study published online Aug. 9 in Diabetes Care.
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Prurigo Nodularis Associated With Mental Health Disorders
FRIDAY, Aug. 23, 2019 (HealthDay News) — Prurigo nodularis (PN) is associated with mental health disorders, systemic illnesses, and HIV infection, according to a study published online Aug. 15 in the Journal of Investigative Dermatology.
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Reduction in PTSD Symptoms Linked to Decrease in T2DM
FRIDAY, Aug. 23, 2019 (HealthDay News) — Clinically meaningful reductions in posttraumatic stress disorder (PTSD) symptoms are associated with a decrease in the risk for type 2 diabetes, according to a study published online Aug. 21 in JAMA Psychiatry.
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Online Information About Diabetic Retinopathy Is Poor
THURSDAY, Aug. 22, 2019 (HealthDay News) — Free online information about diabetic retinopathy is of poor quality, varying accuracy, and low readability, according to a study published online Aug. 22 in JAMA Ophthalmology.
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More Physical Activity at Any Intensity May Reduce Mortality
THURSDAY, Aug. 22, 2019 (HealthDay News) — For middle-aged and older adults, more physical activity at any intensity and less sedentary time are associated with a reduced risk for premature mortality, according to a review published online Aug. 21 in The BMJ.
Type 2 Diabetes Risk Up With Inflammatory Bowel Disease
THURSDAY, Aug. 22, 2019 (HealthDay News) — Patients with inflammatory bowel disease (IBD) have an increased risk for type 2 diabetes, according to a study published online Aug. 5 in Clinical Gastroenterology and Hepatology.
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Type 2 Diabetes Associated With Poorer Outcomes in Heart Failure
THURSDAY, Aug. 22, 2019 (HealthDay News) — For patients with heart failure, type 2 diabetes is associated with structural changes in the heart, poorer quality of life, and increased mortality, according to a study published online Aug. 21 in the Journal of the American Heart Association.
Type 2 Diabetes May Impact Sleep in Middle-Aged Women
WEDNESDAY, Aug. 21, 2019 (HealthDay News) — Middle-aged women with type 2 diabetes mellitus (T2DM) have more sleep disturbances than women without diabetes, even when accounting for menopause and other health issues, according to a study published online Aug. 12 in Menopause.
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Women With Diabetes More Likely Than Men to Not Take Meds as Prescribed
WEDNESDAY, Aug. 21, 2019 (HealthDay News) — Women with diagnosed diabetes are more likely than men to not take their medications as prescribed, according to an August data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.
Taking Buprenorphine for Opioid Use Disorder May Up Other Med Compliance
WEDNESDAY, Aug. 21, 2019 (HealthDay News) — Using buprenorphine to treat opioid use disorder (OUD) may increase adherence to treatments for other chronic conditions, according to a study published in the September issue of Medical Care.
Family History of Diabetes Tied to Higher BMD in Normoglycemia
WEDNESDAY, Aug. 21, 2019 (HealthDay News) — Postmenopausal women with normoglycemia with a first-degree family history of diabetes (FHD) have elevated bone mineral density (BMD), according to a study published online Aug. 19 in Menopause.
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Association for Diabetes, Stroke Risk Varies by Age, Race, Sex
TUESDAY, Aug. 20, 2019 (HealthDay News) — The magnitude of the association of diabetes with stroke risk varies by age, race, and sex, according to a study published online Aug. 7 in Diabetes Care.
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Hypoglycemia Up With Intensive Glucose-Lowering Therapy
MONDAY, Aug. 19, 2019 (HealthDay News) — Intensive glucose-lowering therapy is prevalent among U.S. adults with diabetes and results in hospitalizations and emergency department visits for hypoglycemia, according to a study published online Aug. 15 in the Mayo Clinic Proceedings.
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Diabetes Education, Support Cuts Hypoglycemia Risk
FRIDAY, Aug. 16, 2019 (HealthDay News) — Diabetes self-management education and support can cut hypoglycemia risk, according to a review published in the August issue of The Diabetes Educator.
FDA Proposes Graphic Warning Labels on Cigarettes
THURSDAY, Aug. 15, 2019 (HealthDay News) — Smokers would have to get past some gruesome imagery to purchase a pack of cigarettes under a new rule proposed Thursday by the U.S. Food and Drug Administration.
Advertising Can Promote Interest in Health-Related Research
THURSDAY, Aug. 15, 2019 (HealthDay News) — Advertising current local health-related research using large TV monitors in emergency department waiting rooms can increase the short-term interest in health-related research, according to a study published online Aug. 1 in BMJ Open.
2005-2016 Saw No Improvement in Diabetes Care Cascade
THURDAY, Aug. 15, 2019 (HealthDay News) — From 2005 to 2016, there was no improvement in the diabetes care cascade, according to a study published online Aug. 12 in JAMA Internal Medicine.
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Burden of Obesity-Associated Cancers Shifted to Younger Age Groups
THURSDAY, Aug. 15, 2019 (HealthDay News) — From 2000 to 2016, there was a shift of the obesity-associated cancer (OAC) burden to younger age groups, according to a study published online Aug. 14 in JAMA Network Open.
Model Predicts Hypoglycemia Risk in Adults With Diabetes
THURSDAY, Aug. 15, 2019 (HealthDay News) — In a study published online Aug. 1 in Current Medical Research and Opinion, a predictive model is presented for hypoglycemia that combines nearly all known and readily assessed risk factors for hypoglycemia such as infection, non-long-acting insulin, and dementia.
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Low Muscle Mass in the Arms, Legs Tied to Mortality in Elderly
WEDNESDAY, Aug. 14, 2019 (HealthDay News) — Low muscle mass is associated with all-cause and cardiovascular mortality risk in the elderly, according to a study published in the July issue of the Journal of Bone and Mineral Research.
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Adult Weight Gain Likely Explains Link Between Parity, T2DM Risk
WEDNESDAY, Aug. 14, 2019 (HealthDay News) — The seeming association between parity and risk for type 2 diabetes among postmenopausal women is likely explained by adult weight gain, according to a study published online Aug. 7 in Obstetrics & Gynecology.
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Gluten Intake, Celiac Disease Linked in Genetically Predisposed
WEDNESDAY, Aug. 14, 2019 (HealthDay News) — For children at increased risk, increased gluten intake during the first five years of life is associated with an elevated incidence of celiac disease autoimmunity and celiac disease, according to a study published in the Aug. 13 issue of the Journal of the American Medical Association.
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TSH Elevated in 6 Percent of Psychiatrically Hospitalized Youth
WEDNESDAY, Aug. 14, 2019 (HealthDay News) — About 6 percent of psychiatrically hospitalized youth have abnormal thyroid-stimulating hormone (TSH) measures, according to a study published online Aug. 6 in the Journal of Clinical Psychiatry.
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CDC: Prescription Drug Use Similar in United States, Canada
WEDNESDAY, Aug. 14, 2019 (HealthDay News) — Use of prescription drugs is similar in the United States and Canada, with almost 70 percent of adults aged 40 to 79 years using at least one prescription drug, according to an August data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.
Non-Hospital-Based Provider-to-Patient Telehealth Use Growing
TUESDAY, Aug. 13, 2019 (HealthDay News) — Use of non-hospital-based provider-to-patient telehealth grew almost 1,400-fold from 2014 to 2018, according to a FAIR Health White Paper.
General, Abdominal Adiposity Linked to Mortality in Mexicans
TUESDAY, Aug. 13, 2019 (HealthDay News) — General and abdominal adiposity are associated with mortality in a population of Mexican adults, according to a study published online Aug. 13 in the Annals of Internal Medicine.
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Type 1 Diabetes Misdiagnosed in One-Fourth of Children, Adults
TUESDAY, Aug. 13, 2019 (HealthDay News) — Type 1 diabetes diagnosis is missed less frequently when patients present during childhood or adolescence, but unlike in adults, misdiagnosis in childhood is associated with an increased likelihood of diabetic ketoacidosis (DKA), according to a study published in the July issue of Clinical Diabetes.
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One-Third of Physicians Will Take 10+ Years to Pay Off Debt
MONDAY, Aug. 12, 2019 (HealthDay News) — Nearly two-thirds of actively practicing physicians are still carrying medical school debt, according to the Medical School Debt Report 2019, published by the staffing firm Weatherby Healthcare.
Medical School Debt Report 2019
Use of Technology Now Included in Standards of Diabetes Care
MONDAY, Aug. 12, 2019 (HealthDay News) — A section on the use of technology in the management of diabetes has been added to the American Diabetes Association Standards of Medical Care in Diabetes; a clinical guideline summary was published online Aug. 13 in the Annals of Internal Medicine.
Few at Risk for Diabetes Report Being Informed by Provider
MONDAY, Aug. 12, 2019 (HealthDay News) — Few patients with undiagnosed prediabetes are told that they are at high risk for diabetes, according to a study published in the July issue of Clinical Diabetes.
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Nurse-Led Quality Initiative Cuts Hypoglycemia in ICU Patients
FRIDAY, Aug. 9, 2019 (HealthDay News) — Nurse-driven root cause analysis is associated with a substantial reduction in hypoglycemia in the intensive care unit, according to a study published in the August issue of in Critical Care Nurse.
HbA1c, BMI Linked to Stillbirth Risk in Women With Diabetes
FRIDAY, Aug. 9, 2019 (HealthDay News) — Higher maternal hemoglobin A1c (HbA1c) levels are associated with increased risk for stillbirth among women with type 1 diabetes, while higher BMI increases risk for women with type 2 diabetes, according to a study published online July 29 in Diabetologia.
Guidelines Issued for Managing Hidradenitis Suppurativa
FRIDAY, Aug. 9, 2019 (HealthDay News) — In a two-part guideline, published in the July issue of the Journal of the American Academy of Dermatology, the United States and Canadian Hidradenitis Suppurativa Foundations present recommendations for the diagnosis, evaluation, and management of hidradenitis suppurativa.
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Children With Type 1 Diabetes Have Poorer Educational Outcomes
THURSDAY, Aug. 8, 2019 (HealthDay News) — Children with type 1 diabetes have worse education and health outcomes than their peers, according to a study published online July 15 in Diabetes Care.
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Medicare Spending on Essential Medicines Up 116 Percent From 2011 to 2015
WEDNESDAY, Aug. 7, 2019 (HealthDay News) — Spending associated with essential medicines grew substantially from 2011 to 2015 for Medicare Part D beneficiaries, according to a study published online July 17 in The BMJ.
Recommendations Developed for Obesity Hypoventilation Syndrome
WEDNESDAY, Aug. 7, 2019 (HealthDay News) — In an official American Thoracic Society clinical practice guideline, published in the Aug. 1 issue of the American Journal of Respiratory and Critical Care Medicine, recommendations are presented to guide management and improve outcomes for patients with obesity hypoventilation syndrome (OHS).
Addition of Sotagliflozin for T1DM Alters Renal Hemodynamics
WEDNESDAY, Aug. 7, 2019 (HealthDay News) — Sotagliflozin (SOTA), a dual sodium-glucose cotransporter 1 inhibitor (SGLT1i) and SGLT2i, is associated with short- and long-term renal hemodynamic changes in patients with type 1 diabetes, according to a study published online Aug. 1 in Diabetes Care.
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Lifestyle Counseling Frequency, CV Outcomes Linked in Diabetes
TUESDAY, Aug. 6, 2019 (HealthDay News) — For hyperglycemic adults with diabetes, a higher frequency of lifestyle counseling is associated with a lower incidence of a composite outcome of death and cardiovascular events, according to a study published online Aug. 1 in Diabetes Care.
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Bone Health Management Key in Childhood Cancer Survivors
TUESDAY, Aug. 6, 2019 (HealthDay News) — As part of a literature review, published in the June issue of the Annals of Oncology, recommendations are presented for the management of bone health in survivors of childhood cancer.
Study Explores Dose Ranges for Efpeglenatide in Early T2DM
MONDAY, Aug. 5, 2019 (HealthDay News) — Efpeglenatide once weekly leads to dose-dependent reductions in glucose and body weight in patients with early type 2 diabetes, according to a phase 2 study published online July 18 in Diabetes Care.
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BP, Waist Circumference, Lipids Should Be Measured Regularly
MONDAY, Aug. 5, 2019 (HealthDay News) — Blood pressure, waist circumference, fasting lipid profile, and blood glucose should be measured regularly to identify atherosclerotic cardiovascular disease (ASCVD) and type 2 diabetes mellitus (T2DM), according to guidelines published online July 31 in the Journal of Clinical Endocrinology & Metabolism.
Mediterranean Eating Plan May Help Keep T2DM Patients Off Meds
FRIDAY, Aug. 2, 2019 (HealthDay News) — A Mediterranean eating plan (Med-EatPlan) plus extra virgin olive oil (EVOO) may delay the need for first glucose-lowering medication among participants with type 2 diabetes, according to a study published in the August issue of Diabetes Care.
Brand-Brand Competition Has Not Cut Prices in Pharma Market
FRIDAY, Aug. 2, 2019 (HealthDay News) — Brand-brand competition in the U.S. pharmaceutical market has not lowered drug list prices, according to a review published online July 30 in PLOS Medicine.
Trump Admin Announces Plan to Allow Drug Imports From Canada
THURSDAY, Aug. 1, 2019 (HealthDay News) — Americans could import less expensive prescription drugs from Canada under a plan being developed by the Trump administration.
HHS Press Release
PhRMA Statement
Early Menarche Linked to Risk for T2DM in Rural Chinese Women
THURSDAY, Aug. 1, 2019 (HealthDay News) — For rural Chinese women, a history of early menarche is associated with an increased risk for developing type 2 diabetes mellitus (T2DM), with the correlation partially mediated by adult body mass index (BMI), according to a study published online July 29 in Menopause.
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Childhood BMI, HDL-C Variability May Up Later-Life Diabetes Risk
THURSDAY, Aug. 1, 2019 (HealthDay News) — High variability in body mass index (BMI) and high-density lipoprotein cholesterol (HDL-C) during childhood are associated with an increased risk for later-life diabetes, according to a study published online July 18 in Diabetes Care.
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