Data regarding the treatment of periorificial dermatitis (POD) with topical calcineurin inhibitors (TCI) in the pediatric population are limited.To assess the clinical utility of TCI in pediatric patients with POD.A...Read More
Childhood-onset lupus erythematosus panniculitis (LEP) is a rare and chronic disfiguring disease. A paucity of literature exists on the clinical manifestations of this disease and how best to treat it.To describe the clinical...Read More
Comparison of Tightly Controlled Dose Reduction of Biologics With Usual Care for Patients With Psoriasis: A Randomized Clinical Trial.
Biologics revolutionized the treatment of psoriasis. Biologics are given in a fixed dose, but lower doses might be possible.To investigate whether dose reduction (DR) of biologics in patients with stable psoriasis is noninferior...Read More
Hyperbaric oxygen (HBO) therapy as an effective approach to the treatment of patients with severe idiopathic sudden sensorineural hearing loss.
The potential etiology of idiopathic sudden sensorineural hearing loss (ISSNHL) is cochlear ischemia, therefore, hyperbaric oxygen (HBO) therapy is a promising treatment, particularly in patients with severe hearing loss...Read More
Quantitative analysis of revascularization in ischemic moyamoya disease via whole-brain computed tomography perfusion: A retrospective single-center study.
Ischemic moyamoya disease (MMD) can be treated with the revascularization of superficial temporal artery to middle cerebral artery (STA-MCA) bypass combined with encephalo-duro-arterio-myo-synangiosis (EDAMS) effectively. The...Read More
Potential Therapeutic Application of Zinc Oxide Nanoflowers in Cerebral Ischemia Rat Model Through Neuritogenic and Neuroprotective Properties.
Neuritogenesis, a complex process of sprouting of neurites, plays vital role in structural and functional restoration of cerebral ischemia injured neuronal tissue. Practically, there is no effective long-term treatment strategy...Read More
Inflammasomes are recognized as key components of the innate immune response in sepsis. We aimed to describe the transcriptional expression of nucleotide-binding domain, leucine-rich repeat-containing receptor, pyrin...Read More
To investigate the potential utility of serum uncoupling protein-2 (UCP2) level as a biomarker in septic patients.Critically ill patients with diagnoses of sepsis – sepsis non-shock group (n = 20) and septic shock group...Read More
Long-term mortality and outcome in hospital survivors of septic shock, sepsis, and severe infections: The importance of aftercare.
Patients with severe infections and especially sepsis have a high in-hospital mortality, but even hospital survivors face long-term sequelae, decreased health-related quality of life, and high risk of death, suggesting a great...Read More