As endoscopic management of GERD increases, researchers aimed to examine the available evidence on the benefits of endoscopic and minimally invasive surgeries for GERD. Investigators reviewed evidence from 22 studies, analyzing outcomes based on symptoms and objective criteria reported in each. They tabulated inclusion and exclusion criteria; study duration; intervention outcomes, under subjective (symptom scores, quality of life, and change in proton pump inhibitor use) and objective (pH parameters, endoscopic signs, and lower esophageal sphincter pressure changes) groupings; and adverse events. Most studies demonstrated symptomatic and objective improvement of GERD with the device therapies, and adverse events were minimal. However, normalization of acid exposure arose in approximately 50% of patients and, for several modalities, long-term durability is uncertain, according to the study team.
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