Advertisement

 

 

Bivariate longitudinal data analysis: a case of hypertensive patients at Felege Hiwot Referral Hospital, Bahir Dar, Ethiopia.

Bivariate longitudinal data analysis: a case of hypertensive patients at Felege Hiwot Referral Hospital, Bahir Dar, Ethiopia.
Author Information (click to view)

Workie DL, Zike DT, Fenta HM,


Workie DL, Zike DT, Fenta HM, (click to view)

Workie DL, Zike DT, Fenta HM,

Advertisement
Share on FacebookTweet about this on TwitterShare on LinkedIn

BMC research notes 2017 12 0810(1) 722 doi 10.1186/s13104-017-3044-4
Abstract
OBJECTIVE
Longitudinal data are often collected to study the evolution of biomedical markers. The study of the joint evolution of response variables concerning hypertension over time was the aim of this paper. A hospital based retrospective data were collected from September 2014 to August 2015 to identify factors that affect hypertensive. The joint mixed effect model with unstructured covariance was fitted. A total of 172 patients screened for antihypertensive drugs treated were longitudinally considered from Felege Hiwot referral.

RESULTS
The joint mixed effect model with unstructured covariance (AIC: 12,236.9 with [Formula: see text] = 1007.8, P < 10-4) was significantly best fit to the data. The correlation between the evolutions of DBP and SBP was 0.429 and the evolution of the association between responses over-time was found 0.257. Among all covariates included in joint-mixed-effect-models, sex, residence, related disease and time were statistically significant on evolution of systolic and diastolic blood pressure. The joint modeling of longitudinal bivariate responses is necessary to explore the association between paired response variables like systolic and diastolic blood pressure. Fitting joint model with modern computing method is recommended to address questions for association of the evolutions with better accuracy.

Submit a Comment

Your email address will not be published. Required fields are marked *

20 − 14 =

[ HIDE/SHOW ]