Influenza and other respiratory viruses 2018 04 06() doi 10.1111/irv.12557
Influenza and respiratory syncytial virus (RSV) infections are responsible for substantial global morbidity and mortality in young children and elderly individuals. Estimates of the burden of influenza- and RSV-associated hospitalization are limited in Africa.
We conducted hospital-based surveillance for laboratory-confirmed influenza- and RSV-associated severe acute respiratory illness (SARI) at one hospital and a retrospective review of SARI hospitalizations in five hospitals situated in Antananarivo during 2011-2016. We estimated age-specific rates (per 100,000 population) of influenza- and RSV-associated SARI hospitalizations for the Antananarivo region and then extrapolated these rates to the national level.
Overall the mean annual national number of influenza-associated SARI hospitalizations for all age groups was 6,609 (rate: 30.0); 4,468 (rate: 127.6) and 2,141 (rate: 11.6) among individuals aged <5 and ≥5 was respectively. For these same age groups, the mean annual number of RSV-associated SARI hospitalizations was 11,768 (rate: 53.4), 11,299 (rate: 322.7) and 469 (rate: 2.5), respectively. CONCLUSION
The burden of influenza- and RSV-associated SARI hospitalization was high among children aged <5 years. These first estimates for Madagascar will enable government to make informed evidence-based decisions when allocating scarce resources and planning intervention strategies to limit the impact and spread of these viruses. This article is protected by copyright. All rights reserved.