Mortality rates after the development of cancer are higher among people with HIV, according to study results published in AIDS. Qianlai Luo, PhD, and colleagues examined registry data to identify incident cancers and deaths among people with HIV in 11 US regions from 2006-2015. Among 466,234 people with HIV, 5.5% developed cancer during the study period. Nationally, approximately 134,986 years of life were lost to cancer of all types from 2006- 2015 among people with HIV, representing 9.6% of total years of life lost to all causes. Non-Hodgkin lymphoma, Kaposi sarcoma, anal cancer, and lung cancer contributed to 45% of total years of life lost to cancer. The biggest segments of total years of life lost were men who have sex with men and people with HIV aged 40-59. The findings provide opportunities to decrease cancer mortality through improved access to ART, prevention, and screening, according to Dr. Luo and colleagues.