This study states that Heavy cannabis use is known to have an adverse impact on cardiovascular and cerebrovascular outcomes in the general population. The objective of the present study was to determine the perioperative risk of cannabis use disorder (CUD) in vascular surgery patients. Using the National Inpatient Sample (2006-2015), we conducted a retrospective cohort study of patients who had undergone one of six The primary outcome was perioperative myocardial infarction (MI). The secondary outcomes included stroke, sepsis, deep vein thrombosis, pulmonary embolus, acute kidney injury, respiratory failure, mortality, total cost, and length of stay. We obtained similar results in a sensitivity analysis that included the complete unmatched cohort and adjusted for confounding using logistic regression models to account for the survey design, although the endpoints of sepsis and stroke failed to reach statistical significance after correcting for multiple testing.

CUD was associated with a significantly greater incidence of perioperative MI in vascular surgery patients. Those with CUD had a greater incidence of perioperative stroke when undergoing carotid endarterectomy. However, because of the limitations in administrative data, this could reflect a true effect or a selection bias.

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