FRIDAY, Aug. 10, 2018 (HealthDay News) — For adults aged 60 to 64 years, greater light physical activity (PA) and moderate-to-vigorous intensity PA and less sedentary time are associated with more favorable cardiovascular profiles, according to a study published online Aug. 8 in the Journal of the American Heart Association.

Ahmed Elhakeem, Ph.D., from the University of Bristol in the United Kingdom, and colleagues examined the correlation of objectively measured PA and sedentary time with cardiovascular disease biomarkers among 795 men and 827 women aged 60 to 64 years. Overall PA energy expenditure and time spent sedentary, in light PA, and in moderate-to-vigorous intensity PA were assessed using combined heart rate and movement sensors worn for five consecutive days. Each PA parameter was related to inflammatory, endothelial, and adipokine markers extracted from fasting blood samples.

The researchers found that there were associations for greater time in light PA and moderate-to-vigorous intensity PA and less sedentary time with more favorable biomarker levels. These differences were greater for women than men for C-reactive protein, interleukin-6, and leptin. In women versus men, fat mass mediated a greater proportion of these associations.

“Greater light PA and moderate-to-vigorous intensity PA and less sedentary time in early old age were associated with more favorable cardiovascular biomarker profiles,” the authors write. “Fat mass partially mediated these associations but more strongly in women than men, which explained sex differences.”

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