Cardiovascular disease (CVD) is the leading cause of mortality and morbidity around the world. While the worse-effected individuals from CVD are seniors aged 65 and more, the incidence of premature CVD mortality (age 25-64 years) is also on the rise. The objective of this study is to evaluate the chances of premature mortality in individuals with CVD.

This is a descriptive study that included all CVD deaths among individuals aged 25-64 years. Country-level factors, like rurality, smoking, obesity, and diabetes, were included, and the primary outcome was the risk of CVD mortality.

The study included a total of 2.3 million CVD deaths occurred among individuals aged 25-64 years. Black people had the highest CVD mortality rates, followed by American Indian and Alaskan native individuals. The risk of mortality increased significantly among those aged 25-49 years. In white individuals, the rates of mortality were unhindered among women aged 25-49 years. The increase in mortality rates was significant in the following CVD subtypes: ischemic heart disease and hypertensive heart disease. A high prevalence of diabetes was associated with the highest risk of CVD mortality.

The findings suggested an increase in premature CVD mortality in American Indians and Alaskan natives, with a rise in deaths from ischemic heart disease and hypertensive heart disease.

Ref: https://jamanetwork.com/journals/jamacardiology/fullarticle/2752889?resultClick=1