Link Between Allergy History & Post-COVID-19 Vaccination Allergic Reactions
In December 2020, the FDA granted emergency use authorization for mRNA COVID-19 vaccines from...
Allergy & Immunology General
Pregnancy exposure to phthalates and DNA methylation in male placenta – An epigenome-wide association study.
Exposure to phthalates during pregnancy may alter DNA methylation in the placenta, a crucial organ for the growth and development of the fetus.We studied associations between urinary concentrations of phthalate biomarkers during...
Lower viral loads in rhinovirus-challenged allergic subjects despite reduced innate immunity.
Viral infections, especially those caused by rhinovirus, are the most common cause of asthma exacerbations. Previous studies have argued that impaired innate anti-viral immunity and, as a consequence, more severe infections...
Distribution of chronic cough phenotypes in the general population: A cross-sectional analysis of the LEAD cohort in Austria.
Recent guidelines consider chronic cough to be a unique clinical entity with different phenotypes. We aimed to investigate them in a general population and to describe prevalence, distribution, and characteristics of these...
Semaphorin-3A: a promising therapeutic tool in allergic rhinitis.
Semaphorin-3A (Sema-3A), a secreted member of the semaphorin family, is well known for playing regulatory functions at all stages of the immune response. Sema-3A transduces signals by binding to its cognate receptors, namely,...
A phage virus-based electrochemical biosensor for highly sensitive detection of ovomucoid.
Whole peptide-displayed phage particles are promising alternatives to antibodies in sensor development; however, greater control and functionalization of these particles are required. In this study, we aimed to identify and...
HSP60 regulates the cigarette smoke-induced activation of TLR4-NF-κB-MyD88 signalling pathway and NLRP3 inflammasome.
Chronic obstructive pulmonary disease (COPD) is characterized by increased cellular stress and inflammation. Heat shock protein 60 (HSP60) is a highly conserved stress protein that acts as a cellular “danger” signal...
CCR3 gene knockout in bone marrow cells ameliorates combined allergic rhinitis and asthma syndrome (CARAS) by reducing airway inflammatory cell infiltration and Th2 cytokines expression in mice model.
The present study aims to investigate the effects of CCR3 gene knockout in bone marrow cells (CCR3-KO) on the mouse model of combined allergic rhinitis and asthma syndrome (CARAS). It was found that CCR3-KO significantly reduced...
Three phlorotannins from Sargassum carpophyllum are effective against the secretion of allergic mediators from antigen-stimulated rat basophilic leukemia cells.
Sargassum carpophyllum (Sargassaceae) is a brown seaweed that contains phlorotannins, which are phloroglucinol polymers with reported anti-inflammatory activities. The phlorotannins...
Individual participant data meta-analysis with mixed-effects transformation models.
One-stage meta-analysis of individual participant data (IPD) poses several statistical and computational challenges. For time-to-event outcomes, the approach requires the estimation of complicated nonlinear mixed-effects models...
A population-based study of 92 clinically recognised risk factors for heart failure: co-occurrence, prognosis and preventive potential.
Primary prevention strategies for heart failure(HF) have had limited success, possibly due to a wide range of underlying risk factors(RFs). Systematic evaluations of the prognostic burden and preventive potential across this...
Relationship between montelukast and behavioral problems in preschool children with asthma.
There is insufficient clarity regarding whether or not drugs used in asthma cause behavioral problems in children.A total of 155 individuals, categorized into an asthma group (n = 95) and a control group (n = 60), were enrolled...
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