Patients with inflammatory bowel disease are at increased risk of colorectal neoplasia (CRN) due to mucosal inflammation. As current surveillance guidelines form a burden on patients and healthcare costs, stratification of...
The β-adrenergic receptor (βAR) is a member of the G protein-coupled receptor (GPCR) family that is an important drug target for asthma and COPD. Clinical studies coupled with biochemical data have identified a critical receptor...
Exercise induced bronchoconstriction (EIBc) is a recognised response to exercise in asthmatics and athletes but is less well understood in an unselected broad population. Exercise induced bronchodilation (EIBd) has received even...
The major mast cell prostanoid PGD is targeted for therapy of asthma and other diseases because the biological actions include bronchoconstriction, vasodilation and regulation of immune cells mediated by three different...
Allergic asthma affects more women than men. It is mediated partially by IL-4/IL-13-driven polarization of monocyte-derived macrophages in the lung. We tested whether sex differences in asthma are due to differential IL-4...
Probiotics have garnered considerable attention as an intervention for various conditions common to otolaryngology. The purpose of this review is to evaluate the current literature to offer recommendations about the safety and...
Previous studies have shown that sleep and allergic rhinitis (AR) is closely associated, bidirectionally affecting each other. Adolescence is a period that adequate sleep is essential, and the burden of AR increases, both of...
Respiratory tract viruses are the second most common cause for olfactory dysfunction. As we learn more about the effects of the severe acute respiratory syndrome coronavirus (SARS-CoV-2), with the recognition that olfactory...
Dupilumab has demonstrated efficacy with acceptable safety in clinical trials in patients with moderate-to-severe atopic dermatitis (AD).To assess dupilumab’s impact on asthma and sinonasal conditions in adult patients...
The use of in vivo and ex vivo diagnostic tools for delayed immune-mediated adverse drug reactions (IM-ADR) is currently ill defined.To determine if the combination of skin testing and/or interferon-γ (IFN-γ) enzyme-linked...
The specific benefits of aerobic exercises in smoking cessation are unclear, as they have different characteristics, intensities, and durations. The purpose of this systematic review with meta-analysis was to evaluate the...
Current standards for conducting spirometry examinations recommend that the ventilation manoeuvres needed in pulmonary function testing are carried out repeatedly during the sessions. Chest electrical impedance tomography (EIT)...
