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Asthma

Mental health in patients with asthma: A population-based case-control study.

Feb 07, 2022

This study's objectives were to compare the prevalence of mental disorders and consumption of psychiatric medications in asthmatic subjects with non-asthmatic controls and identify risk factors associ...

The effect of vitamin D on GATA3 gene expression in peripheral blood mononuclear cells in allergic asthma.

Jan 31, 2022

Asthma is becoming a major health problem in many countries. Immune responses in allergic asthma, as the most prevalent asthmatic phenotype, are mediated mostly by a subtype of T lymphocytes referred ...

Allergen Provocation Tests in Respiratory Research: Building on 50 Years of Experience.

Jan 31, 2022

Allergen provocation test is an established model of allergic airway diseases, including asthma and allergic rhinitis, allowing the study of allergen-induced changes in respiratory physiology and infl...

Lung function at school age in infants with lower respiratory tract infections with and without wheezing: a birth cohort study.

Jan 24, 2022

To evaluate the relationship between lower respiratory tract infections (LRTI), in the first 2 years of life and lung function at school age in the Piccolipiù birth cohort (Italy).Data on LRTI (docto...

Lower viral loads in rhinovirus-challenged allergic subjects despite reduced innate immunity.

Jan 17, 2022

Viral infections, especially those caused by rhinovirus, are the most common cause of asthma exacerbations. Previous studies have argued that impaired innate anti-viral immunity and, as a consequence,...

Distribution of chronic cough phenotypes in the general population: A cross-sectional analysis of the LEAD cohort in Austria.

Jan 17, 2022

Recent guidelines consider chronic cough to be a unique clinical entity with different phenotypes. We aimed to investigate them in a general population and to describe prevalence, distribution, and ch...

Relationship between montelukast and behavioral problems in preschool children with asthma.

Jan 03, 2022

There is insufficient clarity regarding whether or not drugs used in asthma cause behavioral problems in children.A total of 155 individuals, categorized into an asthma group (n = 95) and a control gr...

Liquiritigenin enhances cyclic adenosine monophosphate production to mitigate inflammation in dendritic cells.

Dec 27, 2021

This study aims to dissect the mechanism of traditional Chinese medicinal herbs against asthma; we chose to first focus on the main chemical components of licorice to investigate their contribution to...

Prevalence of Gastroesophageal Disease and Associated Risk Factors Among the Population in Al-Qunfudah.

Dec 20, 2021

Background and objective Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal diseases worldwide. It causes an unpleasant effect on patients' lives and may lead to serious...

Evaluation of exercise-induced bronchoconstriction and rhinitis in adolescent elite swimmers.

Dec 20, 2021

Exercise-induced bronchoconstriction (EIB) without asthma and non-allergic rhinitis is frequently reported in athletes who are facing high-risk of airway dysfunctions such as elite swimmers. Therefore...

Pediatric Obesity-Related Asthma: The Role of Nutrition and Nutrients in Prevention and Treatment.

Nov 29, 2021

Childhood obesity rates have dramatically risen in numerous countries worldwide. Obesity is likely a factor in increased asthma risk, which is already one of the most widespread chronic respiratory pa...

Role of Amygdala in Stress-Induced Upregulation of Airway IL-1 Signaling in Asthma.

Nov 22, 2021

Psychological stress, an important contributor to asthma morbidity, potentiates the immune response to allergen, but the brain mechanisms mediating this response are not fully understood. The amygdala...

[Inhibition of the Notch1/Jagged1 pathway promotes homing of bone mesenchymal stem cells to improve asthma in rats].

Nov 15, 2021

To explore the association of the Notch1/Jagged1 pathway with the homing of mesenchymal stem cells (BMSCs) to regulate Th1/Th2 drift in asthma.Twenty SD rats were randomly divided into normal control ...

Follistatin-Like 1 Induces the Activation of Type 2 Innate Lymphoid Cells to Promote Airway Inflammation in Asthma.

Nov 15, 2021

Asthma is a chronic disease closely related to airway inflammation. It has been proven that type 2 innate lymphoid cells (ILC2s) play an essential role in airway inflammation in asthma. Furthermore, t...

Conference Highlights: ACAAI 2021

Nov 09, 2021

New research was presented at ACAAI 2021, the annual American College of Allergy, Asthma & Immunology Annual Scientific Meeting, held virtually and in New Orleans from November 4-8. The features b...

How to detect young athletes at risk of exercise-induced bronchoconstriction?

Nov 08, 2021

Exercise-induced bronchoconstriction (EIB) is a prevalent condition in elite athletes caused by transient airway narrowing during or after exercise. Young athletes nowadays start early to perform high...

The Impact of High-Deductible Health Plans on Controller Medication Use & Exacerbations in Asthma

Nov 01, 2021

Current guidelines recommend that patients with asthma use controller medications, including inhaled corticosteroids (ICS), leukotriene inhibitors (LTIs), or combination ICS and long-acting β2-agonis...

MiR-18a Inhibits PI3K/AKT Signaling Pathway to Regulate PDGF BB-Induced Airway Smooth Muscle Cell Proliferation and Phenotypic Transformation.

Nov 01, 2021

The increased proliferation and migration of airway smooth muscle cells (ASMCs) is a key process in the formation of airway remodeling in asthma. In this study, we focused on the expression of mircoRN...

Long noncoding RNA PTTG3P/miR-192-3p/CCNB1 axis is a potential biomarker of childhood asthma.

Nov 01, 2021

Increasing evidence suggests that long non-coding RNAs (lncRNAs) affect the regulation of immune responses, airway inflammation, and other pathological processes involved in asthma. LncRNA PTTG3P is a...

Physical fitness of children and youth with asthma in comparison to the reference population : Cross-sectional results of the population-based MoMo study in Germany.

Oct 25, 2021

Physical fitness is an essential marker of health. The literature regarding the question of whether individuals with asthma have reduced physical fitness compared to their non-asthmatic peers is incon...