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Allergy & Immunology General

Down-Regulated Surfactant Protein B (SP-B) in Obese Asthmatics

Apr 22, 2022

Because of the critical role of hydrophobic surfactant protein B (SP-B) in lung function, SP-B was researched in asthmatics to determine if it had a role in developing obesity-induced airway inflammat...

Efficacy of NAAGA Vs Fluorometholone For Treating Allergic Conjunctivitis in an EEC

Apr 22, 2022

During controlled exposures to the airborne birch pollen allergen, Bet v 1, in an environmental exposure chamber (EEC), researchers assessed the non-inferiority of a topical mast cell stabilizer, N-ac...

Mast Cell Activation Test: A New Asset in The Investigation of The Chlorhexidine (CHX) Cross-Sensitization Profile

Apr 22, 2022

For a study, researchers sought to determine if combining the passive mast cell activation (pMAT) with CHX-specific IgE (sIgE) allowed us to display effector cell degranulation in response to alexidin...

Leukocyte Redistribution As Immunological Biomarker of Corticosteroid (CS) Resistance in Severe Asthma

Apr 22, 2022

For a study, the researchers sought to determine if leukocyte redistribution might have been used as a biomarker of disease heterogeneity and a bioindicator of possible corticosteroids (CS) resistance...

Intralymphatic Immunotherapy With One or 2 Allergens Renders Similar Clinical Response in Allergic Rhinitis Patients Due to Birch & Grass Pollen

Apr 22, 2022

Patients with severe birch and timothy allergy were randomized to receive 3 monthly injections of 0.1 ml of birch and 5-grass allergen extracts (10,000 SQ units/ml, ALK-Abelló) placebo, or 5-grass an...

Associations of late-life sleep medication use with incident dementia in the Atherosclerosis Risk in Communities (ARIC) Study.

Apr 18, 2022

Sleep medications may contribute to dementia development or indicate sleep disturbances that are markers of or contributors to neurologic disease. The objective of this study was to examine the use of...

Telemedicine & Self-Administered Therapy for Severe Asthma

Apr 14, 2022

Clinicians should consider extending telemedicine in routine clinical practice to manage severe asthma, as well as other chronic respiratory diseases. Research has shown that patients with seve...

Clinical Characteristics & Response to Dietary Elimination in FPIAP

Apr 04, 2022

Diagnosis of food protein-induced allergic proctocolitis (FPIAP) in infants is based on successive elimination and challenge diets with the suspected triggering food. However, certain facets of dietar...

MAPKinase inhibition after failure of immune checkpoint blockade in patients with advanced melanoma - An evaluation of the multicenter prospective skin cancer registry ADOREG.

Apr 04, 2022

Forty to sixty percent of patients with advanced melanoma show primary resistance to PD-1-based immunotherapy, 30-40% of initial responders also progress. Here, we evaluated the outcome of second-line...

Effects of E-Cigarettes and Vaping in kids and Teenagers With Asthma

Mar 28, 2022

Electronic nicotine delivery systems, such as e-cigarettes, are often perceived as safe compared to traditional cigarettes. However, a growing body of research supports the biological plausibility of ...

The Use of Allergen Exposure Chambers in Immunotherapy

Mar 28, 2022

For a study, researchers sought to reflect on and analyze current evidence of the usefulness of allergen exposure chambers (AEC) for allergy immunotherapy investigations, emphasizing AEC validation, t...

Dietary Approaches To Asthma Prevention in Children

Mar 28, 2022

For a study, researchers provided data on food consumption throughout pregnancy, breastfeeding, and early childhood that may help prevent childhood asthma. The study also discussed how future research...

Children's Asthma Phenotyping and Management Strategies

Mar 28, 2022

By the age of 6, half of all children have wheezing episodes. In addition, recurrent preschool wheezing was linked to early lung function loss and had a long-term influence on airway health, so determ...

Challenges and future directions of Pediatric Asthma

Mar 28, 2022

Asthma is a major public health concern across the world, and epidemiological studies over the last few decades have consistently revealed a large increase in childhood asthma prevalence. The Internat...

Pathogenesis and Management of Aspirin-Exacerbated Respiratory Disease

Mar 28, 2022

For a study, researchers sought to offer a complete account of current knowledge on the pathophysiology of aspirin-exacerbated respiratory disease (AERD) and an update on its therapy. Increased amount...

Role of Glucagon-Like Peptide-1 Receptor in Asthma Management

Mar 28, 2022

For a study, researchers sought to discuss the function of glucagon-like peptide-1 (GLP-1) receptor signaling in lowering lung inflammation and the possible use of GLP-1 receptor agonists (GLP-1RAs) i...

Environmental Exposures and Significance in Adult Allergic Diseases

Mar 28, 2022

Allergic diseases are caused by complicated combinations between genetic predisposition and environmental exposure. Therefore, it was critical to understand how particular environmental exposures led ...

Exposome Mapping in Patients With Chronic Obstructive Pulmonary illness

Mar 28, 2022

A complex combination of genetic, microbial, and environmental variables influences the development and progression of chronic respiratory disorders. For a study, researchers examined the effects of e...

Leukocyte redistribution as immunological biomarker of corticosteroid resistance in severe asthma.

Mar 21, 2022

Earlier studies have suggested that the leukocyte redistribution can be considered as an immunological marker of the clinical response to corticosteroids (CS), representing an easy measurable potentia...

Exploring the Role of Social Determinants in Asthma & Eczema

Mar 14, 2022

Social determinants of health such as low income, costs, disease severity, and insurance status contribute to asthma and eczema disparities and may drive higher hospitalization rates in marginalized m...