Allergy & Immunology General | Physician's Weekly
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Allergy & Immunology General

Propranolol Is Associated with Lower Risk of Incidence of Hepatocellular Carcinoma in Patients with Alcoholic Cirrhosis: A Tertiary-Center Study and Indirect Comparison with Meta-Analysis.

May 28, 2020

Alcoholic cirrhosis (AC) leads to enormous disease burden and occupies a substantial proportion in the etiology of hepatocellular carcinoma (HCC), but scarce attention has been paid to this topic. Bes...

Gastrointestinal involvement of primary skin diseases.

May 28, 2020

Less is known about gastrointestinal (GI) involvement of primary skin diseases due to the difference in embryology, histology, microbiology and physiology between integument and alimentary tract. Esop...

CME: Obstructive Lung Disease: Comparing Inhaler Education Approaches

May 26, 2020

This course discusses a study that explored if the virtual teach-to-goal (TTG) intervention was as effective as in-person TTG education for improving inhaler technique among patients hospitalized with...

A Pediatric CDS Guide to Peanut Allergy

May 26, 2020

Data indicate that peanut allergy is a growing epidemic, with a current prevalence of 2.2%, up from 0.8% in the early 2000s. Evidence suggests that parent and pediatric clinician concerns have grown i...

Major Roadway Proximity & Asthma Severity

May 25, 2020

Research suggests that urban minority children of low socioeconomic status endure disproportionately high asthma morbidity. Although traffic proximity has been associated with adverse respiratory hea...

CME - Conference Highlights: AAAAI 2020

May 20, 2020

This course discusses the key findings of five studies presented at the virtual 2020 American Academy of Allergy Asthma & Immunology Annual Meeting....

Loss of tumor susceptibility gene 101 (TSG101) perturbs endoplasmic reticulum structure and function.

May 19, 2020

Tumor susceptibility gene 101 (TSG101), an ESCRT-I protein, is implicated in multiple cellular processes and its functional depletion can lead to blocked lysosomal degradation, cell cycle arrest, demy...

Importance of adequate diagnostic work-up for correct diagnosis of advanced systemic mastocytosis.

May 19, 2020

Little is known about epidemiology of advanced systemic mastocytosis (advSM).We sought to investigate epidemiologic features and diagnostic pitfalls of advSM in Germany.Therefore, 140 patients from a ...

Add-on omalizumab for inadequately controlled severe pollinosis despite standard-of-care: a randomized study.

May 19, 2020

Cedar pollinosis (CP), a common form of seasonal allergic rhinitis (AR), is a substantial medical problem in Japan due to its high prevalence and severe symptoms. Omalizumab (anti-IgE therapy) has pre...

Ascaridoids in commercial fish: Occurrence, intensity and localization in whole fish and fillets destined for the Belgian market.

May 19, 2020

Anisakidae and Raphidascaridae are marine nematodes present in a wide range of fish hosts, which may cause gastro-intestinal complaints and/or allergy in human, in addition to economic losses for the ...

IL-15 Expression Pattern in Atopic Dermatitis.

May 19, 2020

An increased expression of interleukin (IL)-15, a cytokine with a key role in stimulating innate and adaptive immune cells, such as dendritic cells (DC), natural killer cells, and T cells, has been ob...

Guidance for the Conduct and Reporting of Clinical Trials of Breast Milk Substitutes.

May 12, 2020

Breast milk substitutes (BMS) are important nutritional products evaluated in clinical trials. Concerns have been raised about the risk of bias in BMS trials, the reliability of claims that arise from...

Ovomucoid epitope-specific repertoire of IgE, IgG , IgG , IgA and IgD antibodies in egg allergic children.

May 12, 2020

Egg-white ovomucoid, i.e. Gal d 1, is associated with IgE-mediated allergic reactions in most egg allergic children. Epitope-specific IgE levels have been correlated with the severity of egg allergy, ...

Investigating Viruses During the Transformation of Molecular Biology: Part II.

May 12, 2020

My scientific career started at an extraordinary time, shortly after the discoveries of the helical structure of DNA, the central dogma of DNA to RNA to protein, and the genetic code. Part I of this s...

JAK Inhibition as a New Treatment Strategy for Patients with COVID-19.

May 12, 2020

After the advent of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the outbreak of coronavirus disease 2019 (COVID-19) commenced across the world. Understanding the Immunopathogenesis o...

Anisakiasis: The Importance of Prevention and the Role of Diet Therapy in Allergic Patients.

May 12, 2020

Anisakiasis is a zoonosis of parasitic origin whose diffusion seems to be continuously increasing.The aim of this study was to evaluate the benefits of a fish-free diet in patients allergic to Anisaki...

Radiation pneumonitis after definitive concurrent chemoradiotherapy with cisplatin/docetaxel for non-small cell lung cancer: Analysis of dose-volume parameters.

May 05, 2020

Radiation pneumonitis (RP) is a major pulmonary adverse event of chest radiotherapy. The PACIFIC trial that identified durvalumab as an effective subsequent-line therapy after concurrent chemoradiothe...

Chronic cough in Vocal Cord Dysfunction: Description of a clinical entity.

May 05, 2020

Vocal Cord Dysfunction (VCD) and chronic cough (CC) are challenging conditions which lead to significant quality of life impairment. The underlying mechanisms are poorly understood, but laryngeal dysf...

Osthole alleviates neuropathic pain in mice by inhibiting the P2Y-receptor-dependent JNK signaling pathway.

May 05, 2020

There are many reports about natural products relieving neuralgia. Osthole is the main component of , a natural product that treats rheumatism through the elimination of inflammation and the alleviati...

Single-cell transcription analysis of Plasmodium vivax blood-stage parasites identifies stage- and species-specific profiles of expression.

May 05, 2020

Plasmodium vivax and P. falciparum, the parasites responsible for most human malaria worldwide, exhibit striking biological differences, which have important clinical consequences. Unfortunately, P. v...

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