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Allergy & Immunology

Corticosteroid exposure in eczema: Patient survey findings

May 16, 2023

The following is a summary of the “Corticosteroid exposure and cumulative effects in patients with eczema: Results from a patient survey,” published in the January 2023 issue of Allergy and Clinic...

Biologics for EoE and EGIDs: Improving Treatment Options

May 16, 2023

The following is a summary of the “Biologics in eosinophilic gastrointestinal diseases,” published in the January 2023 issue of Allergy and Clinical Immunology by Dellon et al. There is a s...

In-Flight Epinephrine Use: Frequency & Characteristics

May 15, 2023

The following is a summary of the “Frequency and characteristics of epinephrine use during in-flight allergic events,” published in the January 2023 issue of Allergy and Clinical Immunology by Kod...

Development of a clinical score to estimate pancreatitis-related hospital admissions in patients with a new diagnosis of chronic pancreatitis: the trinity score.

May 15, 2023

The clinical course of chronic pancreatitis is unpredictable and there is no globally accepted score to predict the disease course. We developed a clinical score to estimate pancreatitis-related hospi...

FVC/D identifies pulmonary hypertension and predicts 5-year all-cause mortality in patients with COPD.

May 15, 2023

Pulmonary hypertension (PH) is a common complication of chronic obstructive pulmonary disease (COPD). However, it is unknown whether the ratio of forced vital capacity (FVC) to diffusing lung capacity...

Inhaled drug delivery for the targeted treatment of asthma.

May 15, 2023

Asthma is a chronic lung disease affecting millions worldwide. While classically acknowledged to result from allergen-driven type 2 inflammatory responses leading to IgE and cytokine production and th...

Combined Epimedii Folium and Ligustri Lucidi Fructus with dexamethasone alleviate the proliferation of airway smooth muscle cells by regulating apoptosis/autophagy.

May 15, 2023

Traditional Chinese medicine (TCM) theory believes kidney deficiency is the root cause of chronic refractory asthma with pathological changes of airway remodeling. Our previous experiments confirmed t...

Dimethylglycine, a methionine metabolite, participates in the suppressive effect of methionine on 1-fluoro-2,4-dinitrobenzene-induced dermatitis.

May 15, 2023

Allergic contact dermatitis (ACD) is a common skin disorder caused by contact with allergens. The optimal treatment for ACD is to avoid contact with allergens. However, in some cases, avoiding exposur...

Upregulated expression of Notch1/4 - JAG-1/DLL-1 detected in allergic rhinitis.

May 15, 2023

Allergic rhinitis (AR) is a chronic disease with high prevalence. There are currently many treatments available. However, despite an often good therapeutic response, many patients still report impairm...

Chronic Cough: Global Trial Data & Outcomes

May 11, 2023

The following is a summary of the “Demographic, clinical, and patient-reported outcome data from 2 global, phase 3 trials of chronic cough,” published in the January 2023 issue of Allergy and Clin...

Reviewing the Support of Nasal CSI for CRS

May 10, 2023

The following is a summary of the “Review of evidence supporting the use of nasal corticosteroid irrigation for chronic rhinosinusitis,” published in the January 2023 issue of Allergy and Clinical...

Understanding the Eosinophilic Esophagitis's Complex Pathophysiology

May 09, 2023

The following is a summary of the “Breaking down the complex pathophysiology of eosinophilic esophagitis,” published in the January 2023 issue of Allergy and Clinical Immunology by Underwood, et a...

Treating Eosinophilic Esophagitis During Biologics’ Current State

May 08, 2023

The following is a summary of the “Current state of biologics in treating eosinophilic esophagitis,” published in the January 2023 issue of Allergy and Clinical Immunology by Nhu et al. Whe...

Development and internal validation of nomograms based on plasma metabolites to predict non-small cell lung cancer risk in smoking and nonsmoking populations.

May 08, 2023

Lung cancer has significantly higher incidence and mortality rates worldwide. In this study, we analyzed the metabolic profiles of non-small cell lung cancer (NSCLC) patients and constructed predictio...

An investigation of the internal morphology of asbestos ferruginous bodies: constraining their role in the onset of malignant mesothelioma.

May 08, 2023

Asbestos is a fibrous mineral that was widely used in the past. However, asbestos inhalation is associated with an aggressive type of cancer known as malignant mesothelioma (MM). After inhalation, an ...

Obstructive sleep apnea in asthmatic children: a cross-sectional study about prevalence and risk factors.

May 08, 2023

Primary objectives were to analyze the prevalence of obstructive sleep apnea in (1) boys and girls, and (2) severe asthma versus moderate and mild cases. The authors hypothesized that girls and severe...

Role of adiponectin, resistin and monocyte chemo-attractant protein-1 in overweight/obese asthma phenotype in children.

May 08, 2023

Asthma is a chronic inflammatory disorder of the airways with diverse overlapping pathologies and phenotypes contributing to a significant heterogeneity in clinical manifestations. Obesity may modify ...

Gut microbiota maturity mediates the protective effect of siblings on food allergy.

May 08, 2023

The mechanisms underlying the protective effect of older siblings on allergic disease remain unclear but may relate to the infant gut microbiota.We investigated whether having older siblings decreases...

[Clinical features of IgG4-related lung disease].

May 08, 2023

To explore the clinical features of IgG4-related lung disease. The clinical data of 60 patients diagnosed with IgG4-related lung disease in Peking University People's Hospital from February 2012 to ...

Chronic Cough: Insights from Allergy Specialists

May 05, 2023

The following is a summary of the “Referrals, etiology, prevalence, symptoms, and treatments of chronic cough: A survey of allergy specialists,” published in the December 2022 issue of Allergy and...