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Critical Care General

Integrated multi-omic analysis identifies fatty acid binding protein 4 as a biomarker and therapeutic target of ischemia-reperfusion injury in steatotic liver transplantation.

Feb 12, 2024

Due to a lack of donor grafts, steatotic livers are used more often for liver transplantation (LT). However, steatotic donor livers are more sensitive to ischemia-reperfusion (IR) injury and have a wo...

Genetic, Immunological, and Clinical Features of 830 Patients with Mendelian Susceptibility to Mycobacterial Diseases (MSMD): A Systematic Review.

Feb 12, 2024

Mendelian susceptibility to mycobacterial diseases (MSMD) is a rare clinical syndrome characterized by vulnerability to weakly virulent mycobacterial species, including Bacillus Calmette-Guérin (BCG)...

Use of pus metagenomic next-generation sequencing for efficient identification of pathogens in patients with sepsis.

Feb 12, 2024

The positive detection rate of blood metagenomic next-generation sequencing (mNGS) was still too low to meet clinical needs, while pus from the site of primary infection may be advantageous for identi...

Incidence of tuberculosis (TB) disease in individuals diagnosed with TB infection following screening: a population-based cohort study in South Korea.

Feb 12, 2024

Limited evidence exists regarding the impact of adherence to diverse tuberculosis preventive therapy (TPT) regimens on TB risk in individuals with tuberculosis infections (TBI). This study aimed to ex...

Histological and functional assessment of a Takotsubo cardiomyopathy model established by immobilization stress.

Feb 12, 2024

Takotsubo cardiomyopathy (TTC), also known as stress-induced cardiomyopathy, resembles acute heart failure syndrome but lacks disease-specific diagnosis and treatment strategies. TTC accounts for appr...

Artificial intelligence predictive analytics in heart failure: results of the pilot phase of a pragmatic randomized clinical trial.

Feb 12, 2024

We conducted an implementation planning process during the pilot phase of a pragmatic trial, which tests an intervention guided by artificial intelligence (AI) analytics sourced from noninvasive monit...

Plasma concentrations of histidine-rich glycoprotein in primary graft dysfunction after lung transplantation.

Feb 05, 2024

Histidine-rich glycoprotein has been reported as an anti-inflammatory glycoprotein that inhibits acute lung injury in mice with sepsis and as a prognostic biomarker in patients with sepsis. We investi...

Use of psychoacoustic spectrum warping, decision template fusion, and neighborhood component analysis in newborn cry diagnostic systems.

Feb 05, 2024

Dealing with newborns' health is a delicate matter since they cannot express needs, and crying does not reflect their condition. Although newborn cries have been studied for various purposes, there is...

Human Umbilical Cord Mesenchymal Stem Cell Exosome-derived miR-335-5p Alleviated Lipopolysaccharide-induced Acute Lung Injury by Regulating the m6A Level of ITGβ4 Gene.

Feb 05, 2024

Acute lung injury (ALI) is a serious complication that may accompany severe pneumonia in children. Derived from exosomes of human umbilical cord mesenchymal stem cell exosome (HucMSC-Exo) can contribu...

Neonatal Group B infection at a single center in Al-Madinah Al-Munawarah, Saudi Arabia.

Feb 05, 2024

To determine the occurrence of Group B (GBS) infection in neonates and its associated risk factors in Al-Madinah Al-Munawarah, Saudi Arabia.This retrospective study was carried out at the Maternity a...

Factors affecting duration of stay in the intensive care unit after coronary artery bypass surgery and its impact on in-hospital mortality: a retrospective study.

Feb 05, 2024

Different risk factors affect the intensive care unit (ICU) stay after cardiac surgery. This study aimed to evaluate these risk factors.A retrospective analysis was conducted on clinical, operative, a...

Effect of PCC on outcomes of severe traumatic brain injury patients on preinjury anticoagulation.

Feb 05, 2024

This study aims to evaluate effect of 4-factor PCC on outcomes of severe TBI patients on preinjury anticoagulants undergoing craniotomy/craniectomy.In this analysis of 2018-2020 ACS-TQIP, patients wit...

Immunoregulatory and neutrophil-like monocyte subsets with distinct single-cell transcriptomic signatures emerge following brain injury.

Feb 05, 2024

Monocytes represent key cellular elements that contribute to the neurological sequela following brain injury. The current study reveals that trauma induces the augmented release of a transcriptionally...

Cerebral regional oxygen saturation as a predictive parameter for preoperative heart failure and delayed hemodynamic recovery in transcutaneous aortic valve implantation: a retrospective cohort study.

Feb 05, 2024

This study aimed to investigate the relationship of perioperative cerebral regional oxygen saturation (rSO) with various preoperative clinical variables and hemodynamic changes during transfemoral tra...

Direct oral anticoagulants versus vitamin K antagonists in patients with atrial fibrillation and stage 5 chronic kidney disease under dialysis: A systematic review and meta-analysis of randomized controlled trials.

Jan 29, 2024

In patients with atrial fibrillation (AF) and normal or slightly impaired renal function, the use of direct oral anticoagulants (DOACs) is preferable to vitamin K antagonists (VKAs). However, in patie...

Minimally invasive surgery for esophagogastric junction cancer with Leriche's syndrome-induced ischemic enteritis in the rectum: A case report.

Jan 29, 2024

The incidence of esophagogastric junction cancer has been increasing, leading to growing interest in surgical treatment. Leriche syndrome, characterized by occlusion limited to the infrarenal aorta, h...

Advances in endotoxin analysis.

Jan 29, 2024

The outer membrane of gram-negative bacteria is primarily composed of lipopolysaccharide (LPS). In addition to protection, LPS defines the distinct serogroups used to identify bacteria specifically. F...

Exploration and validation of signature genes and immune associations in septic cardiomyopathy.

Jan 29, 2024

An early and accurate diagnosis of septic cardiomyopathy is vital for improving the overall prognosis of sepsis. In our research, we aimed to identify signature genes and their immune connections in s...

Risk factors and predicting nomogram for the clinical deterioration of non-severe community-acquired pneumonia.

Jan 29, 2024

Currently, there remains insufficient focus on non-severe community-acquired pneumonia (CAP) patients who are at risk of clinical deterioration, and there is also a dearth of research on the related r...

Diagnosis and management of complications following pelvic organ prolapse surgery using a synthetic mesh: French national guidelines for clinical practice.

Jan 29, 2024

Complications associated with pelvic organ prolapse (POP) surgery using a synthetic non-absorbable mesh are uncommon (<5%) but may be severe and may hugely diminish the quality of life of some wome...

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